Table 2

Demographic information for patients with stage III/IV ovarian cancer

Parameter, n (%)All patients with stage III/IV ovarian cancer
(N=5386)
Histology
 High-grade serous carcinoma3249 (60.3)
 High-grade endometrioid carcinoma372 (6.9)
 Other*1765 (32.8)
BRCA
BRCA mutation1427 (26.5)
BRCA wild-type3000 (55.7)
 Not tested959 (17.8)
Homologous recombination deficiency
 Homologous recombination deficient217 (4.0)
 Homologous recombination proficient926 (17.2)
 Not tested4243 (78.8)
Homologous recombination repair
 Homologous recombination repair mutation146 (2.7)
 Homologous recombination repair wild-type1479 (27.5)
 Not tested3761 (69.8)
Tumor cytoreductive surgery
 Optimal tumor cytoreduction1236 (23.0)
 Suboptimal, no surgery, or unknown4150 (77.0)
Response to initial treatment
 Complete response or partial response to initial treatment in patients receiving first-line maintenance1803 (33.5)
 Stable disease or progressive disease to initial treatment in patients receiving first-line maintenance201 (3.7)
 Unknown response to initial treatment in patients receiving first-line maintenance1012 (18.8)
 Did not receive first-line maintenance2370 (44.0)
  • *Other histologies include clear cell carcinoma, low-grade serous carcinoma, low-grade endometrioid carcinoma, mucinous carcinoma, seromucinous carcinoma, and malignant Brenner tumor.