Table 2

Lymph node involvement stratified by myometrial invasion and grade in endometrioid endometrial cancer

ParameterGrade 1 (n=775)Grade 2 (n=428)Grade 3 (n=156)Total (n=1359)
ITCMicroMacroITCMicroMacroITCMicroMacroITCMicroMacro
No MI invasion0/227
(0.0)
0/227
(0.0)
0/227
(0.0)
1/47
(2.1)
0/47
(0.0)
0/47
(0.0)
0/22
(0.0)
0/22
(0.0)
1/22
(4.5)
1/296
(0.3)
0/296
(0.0)
1/296
(0.3)
<50% MI18/453
(4.0)
5/453
(1.1)
2/453
(0.4)
13/255
(5.1)
9/255
(3.5)
4/255
(1.6)
3/65
(4.6)
3/65
(4.6)
1/65
(1.5)
34/773
(4.4)
17/773
(2.2)
7/773
(0.9)
≥50% MI14/95
(14.7)
8/95
(8.4)
7/95
(7.4)
14/126
(11.1)
16/126
(12.7)
14/126
(11.1)
9/69
(13.0)
2/69
(2.9)
10/69
(14.5)
37/290
(12.8)
26/290
(9.0)
31/290
(10.7)
Column total32/775
(4.1)
13/775
(1.7)
9/775
(1.2)
28/428
(6.5)
25/428
(5.8)
18/428
(4.2)
12/156
(7.7)
5/156
(3.2)
12/156
(7.7)
72/1359
(5.3)
43/1359
(3.2)
39/1359
(2.9)
  • Notes: Each cell reports the number of patients with nodal involvement/total number of patients in the cell (cell percentage). For patients who underwent both sentinel lymph node (SLN) biopsy and systematic lymphadenectomy (LND), only data regarding sentinel nodes are reported. It should be noted that 2/1359 (0.1%) with negative SLN had a positive lymph node at systematic LND (both “positive unknown type” at pelvic and/or para-aortic LND, grade 2 with <50% myometrial invasion).

  • ITC, isolated tumor cells; Macro, macrometastases; MI, myometrial invasion; Micro, micrometastases.