Univariable and multivariable Cox regression analysis for overall survival (n=294)
| Overall survival | Univariable | Multivariable | ||
| P value | HR (95% CI) | P value | HR (95% CI) | |
| Age >52 years at diagnosis (vs ≤52 years) | 0.013 | 1.93 (1.50 to 3.24) | 0.001 | 2.47 (1.43 to 4.24) |
| WHO PS: PS 1–4 (vs PS 0) | 0.058 | 1.64 (0.98 to 2.72) | NS | |
| Smoking: current or former smoker (vs never smoked) | 0.914 | 0.97 (0.58 to 1.63) | ||
| Diabetes mellitus (vs no diabetes mellitus) | 0.006 | 2.73 (1.34 to 5.58) | NS | |
| Low socioeconomic status (vs high) | 0.200 | 0.71 (0.42 to 1.20) | ||
| Histology: non-squamous cell (vs squamous cell) | 0.074 | 1.63 (0.95 to 2.79) | 0.004 | 2.24 (1.29 to 3.89) |
| FIGO stage III/IV (vs stage I/II) | <0.001 | 2.58 (1.52 to 4.40) | 0.008 | 2.14 (1.22 to 3.75) |
| N1 (vs N0) | 0.019 | 1.94 (1.12 to 3.37) | 0.001 | 2.64 (1.48 to 4.70) |
| Chemotherapy or hyperthermia (vs no chemotherapy or hyperthermia) | 0.768 | 1.13 (0.51 to 2.48) | ||
| Postoperative radiotherapy (vs primary) | 0.862 | 0.94 (0.48 to 1.86) | ||
| Overall treatment time: <50 (vs ≥50 days) | 0.618 | 1.13 (0.69 to 1.86) | ||
| Malnutrition (vs no malnutrition)* | 0.002 | 2.35 (1.36 to 4.06) | 0.006 | 2.17 (1.24 to 3.78) |
p<0.05 was considered significant.
*Malnutrition at some point in time.
FIGO, International Federation of Gynaecology and Obstetrics; HR, hazard ratio; N0, no pathological lymph nodes; N1, pathological lymph nodes; WHO PS, World Health Organization performance status.