Parameter | Progression-free survival | Overall survival | ||
HR (95% CI) | P value | HR (95% CI) | P value | |
Fagotti_2 | 1.2 (1.1 to 1.3) | 0.00000052 | 1.2 (1.1 to 1.3) | 0.0000017 |
R status | 1.6 (1.2 to 2.1) | 0.002 | 1.7 (1.3 to 2.3) | 0.000094 |
Fagotti_1 | 1.1 (1 to 1.3) | 0.017 | 1.1 (1 to 1.3) | 0.021 |
ECOG | 1.4 (1.1 to 1.9) | 0.02 | 1.8 (1.3 to 2.5) | 0.00016 |
∆Fagotti | 0.92 (0.85 to 1) | 0.045 | 0.92 (0.84 to 1) | 0.046 |
Age | 1 (0.99 to 1) | 0.39 | 1 (0.99 to 1) | 0.13 |
Menopause | 1.2 (0.73 to 2) | 0.45 | 0.95 (0.59 to 1.5) | 0.83 |
BMI | 1 (0.96 to 1.1) | 0.65 | 1 (0.94 to 1.1) | 0.88 |
*Univariate regression analysis of clinical parameters including Fagotti score before (Fagotti_1) and after (Fagotti_2) neoadjuvant chemotherapy, change in Fagotti score (∆Fagotti), surgical resection (R) status, performance status, age, menopausal state, and BMI.
BMI, body mass index; ECOG, Eastern Cooperative Oncology Group performance status.