Table 2

Hazard ratios (HR) of different clinical parameters for survival of patients*

ParameterProgression-free survivalOverall survival
HR (95% CI)P valueHR (95% CI)P value
Fagotti_21.2 (1.1 to 1.3)0.000000521.2 (1.1 to 1.3)0.0000017
R status1.6 (1.2 to 2.1)0.0021.7 (1.3 to 2.3)0.000094
Fagotti_11.1 (1 to 1.3)0.0171.1 (1 to 1.3)0.021
ECOG1.4 (1.1 to 1.9)0.021.8 (1.3 to 2.5)0.00016
∆Fagotti0.92 (0.85 to 1)0.0450.92 (0.84 to 1)0.046
Age1 (0.99 to 1)0.391 (0.99 to 1)0.13
Menopause1.2 (0.73 to 2)0.450.95 (0.59 to 1.5)0.83
BMI1 (0.96 to 1.1)0.651 (0.94 to 1.1)0.88
  • *Univariate regression analysis of clinical parameters including Fagotti score before (Fagotti_1) and after (Fagotti_2) neoadjuvant chemotherapy, change in Fagotti score (∆Fagotti), surgical resection (R) status, performance status, age, menopausal state, and BMI.

  • BMI, body mass index; ECOG, Eastern Cooperative Oncology Group performance status.