Table 3

Three-year and 5 year progression-free survival (PFS) and overall survival (OS) rates by stage group and response to primary treatment*

Response to primary treatmentEarly-stage diseaseLocally advanced diseaseAdvanced diseaseP value
Complete response
 3-year PFS72% (64% to 81%)48% (39% to 57%)28% (7% to 48%)<0.0001
 5-year PFS68% (59% to 78%)42% (33% to 51%)19% (0% to 39%)
 3-year OS91% (86% to 97%)63% (54% to 71%)53% (29% to 77%)<0.0001
 5-year OS78% (69% to 87%)52% (43% to 61%)39% (15% to 64%)
Partial response
 3-year OSNA100% (NA-100%)100% (0% to 100%)0.8651
 5-year OSNA100% (0% to 100%)100% (0% to 100%)
Stable disease
 3-year OSNA13% (0% to 35%)13% (0% to 35%)0.1823
 5-year OSNA13% (0% to 35%)13% (0% to 35%)
Mixed response or progressive disease or new disease
 3-year OS35% (11% to 60%)9% (2% to 17%)3% (0% to 8%)0.0012
 5-year OS21% (0% to 42%)2% (0% to 6%)3% (0% to 8%)
  • *Values in table are rate (95% CI).