Table 3

Ongoing studies in low-grade serous carcinoma

Study namePhaseSettingInterventionIdentifier
NRG-GY019IIIAdjuvantCarboplatin/paclitaxel x6 followed by letrozole maintenance vs letrozole maintenance aloneNCT04095364
LEPRE trialIIIAdjuvantCarboplatin/paclitaxel x6 vs letrozoleNCT05601700
MATAOIIIAdjuvantCarboplatin/paclitaxel followed by letrozole vs placeboNCT04111978
GOG-3026IIRecurrentLetrozole in combination with ribociclibNCT03673124
WO42178/ENGOT-GYN2/GOG-3051/BOUQUETIIRecurrentMultiple biomarker driven armsNCT04931342
IIRecurrentRogorafenib in combination with fulvestrantNCT05113368
The FUCHSia StudyIIRecurrentFulvestrantNCT03926936
PERCEPTIONIIRecurrentCarboplatin-based chemotherapy in combination with pembrolizumabNCT04575961
IIRecurrentLiposomal doxorubicin in combination with peposertibNCT04092270
ENGOT-ov60/GOG-3052/RAMP-201IIRecurrentAvutometinib (VS-6766) in combination with defactinibNCT04625270