Table 1

Patient and disease characteristics at baseline for all patients and by time of diagnosis (period I and period II)

Characteristics	All patients		Patients diagnosed in period I*		Patients diagnosed in period II*		P value
	n=250		n=171		n=79
	N	%	N	%	N	%
Age at diagnosis, median (IQR)	67.0 (59.0–73.0)		67.0 (59.0–72.0)		66.0 (59.0–73.0)		0.973
BMI at diagnosis, kg/m²							0.298
<18.5	8	3.2	3	1.8	5	6.3
≥18.5 and ≤24.9	108	43.2	77	45.0	31	39.2
≥25.0 and ≤29.9	81	32.4	53	31.0	28	35.4
≥30	46	18.4	32	18.7	14	17.7
Unknown	7	2.8	6	3.5	1	1.3
Country of birth (self-reported)							0.877
The Netherlands	192	76.8	133	77.8	59	74.7
Other	7	2.8	5	2.9	2	2.5
Unknown	51	20.4	33	19.3	18	22.8
Educational level† (self-reported)							0.049
Low	70	28.0	56	32.7	14	17.7
Medium	109	43.6	67	39.2	42	53.2
High	6	2.4	5	2.9	1	1.3
Unknown	65	26.0	43	25.1	22	27.8
Parity at diagnosis (self-reported)							0.595
Yes	157	62.8	111	64.9	46	58.2
No	40	16.0	26	15.2	14	17.7
Unknown	53	21.2	34	19.9	19	24.1
Smoking status at diagnosis (self-reported)							0.983
Never smoker	100	40.0	69	40.4	31	39.2
Former smoker	86	34.4	58	33.9	28	35.4
Current smoker	21	8.4	15	8.8	6	7.6
Unknown	43	17.2	29	17.0	14	17.7
Family history of cancer at diagnosis (self-reported)							0.914
Yes	139	55.6	96	56.1	43	54.4
No	67	26.8	46	26.9	21	26.6
Unknown	44	17.6	29	17.0	15	19.0
WHO performance status at diagnosis							0.478
0	142	56.8	97	56.7	45	57.0
1	54	21.6	36	21.1	18	22.8
2	14	5.6	7	4.1	7	8.9
3	3	1.2	3	1.8	–	–
Unknown	37	14.8	28	16.4	9	11.4
Frailty at diagnosis (GFI)							0.890
<4 (non-frail)	114	45.6	76	44.4	38	48.1
≥4 (frail)	47	18.8	33	19.3	14	17.7
Unknown	89	35.6	62	36.3	27	34.2
Histology at diagnosis							0.352
High-grade serous	173	69.2	121	70.8	52	65.8
Low-grade serous	8	3.2	6	3.5	2	2.5
Mucinous	11	4.4	7	4.1	4	5.1
Endometrioid	26	10.4	17	9.9	9	11.4
Clear cell	23	9.2	14	8.2	9	11.4
Carcinosarcoma	4	1.6	1	0.6	3	3.8
Adenocarcinoma NOS	5	2.0	5	2.9	–	–
FIGO stage at diagnosis							0.976
I	40	16.0	28	16.4	12	15.2
II	24	9.6	17	9.9	7	8.9
III	132	52.8	88	51.5	44	55.7
IV	53	21.2	37	21.6	16	20.3
Unknown	1	0.4	1	0.6	–	–

*Period I: January 1, 2016 until July 1, 2018. Period II: July 1, 2018 until January 1, 2020.
†Educational levels were defined as follows: low=primary or secondary education or less; medium=vocational education; high=university or higher education.
BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; GFI, Groningen Frailty Index; IQR, Interquartile range; NOS, not otherwise specified.