Table 4

Patient and disease characteristics at baseline for all patients and by testing status (tested and untested)

Characteristics	All patients		Tested		Untested		P value
	n=250		n=201		n=48
	N	%	N	%	N	%
Age at diagnosis, median (IQR)	67.0 (59.0–73.0)		66.0 (59.0–72.0)		70.0 (61.3–75.0)		0.023
Year of diagnosis							0.497
2016	48	19.2	36	17.9	12	25.0
2017	80	32.0	64	31.8	15	31.3
2018	71	28.4	61	30.3	10	20.8
2019	51	20.4	40	19.9	11	22.9
BMI at diagnosis, kg/m²							0.534
<18.5	8	3.2	5	2.5	3	6.3
≥18.5 and ≤24.9	108	43.2	86	42.8	21	43.8
≥25.0 and ≤29.9	81	32.4	65	32.3	16	33.3
≥30	46	18.4	38	18.9	8	16.7
Unknown	7	2.8	7	3.5	–	–
Country of birth (self-reported)							0.770
The Netherlands	192	76.8	154	76.6	38	79.2
Other	7	2.8	6	3.0	–	–
Unknown	51	20.4	41	20.4	10	20.8
Educational level* (self-reported)							0.399
Low	70	28.0	53	26.4	16	33.3
Medium	109	43.6	92	45.8	17	35.4
High	6	2.4	4	2.0	2	4.2
Unknown	65	26.0	52	25.9	13	27.1
Parity at diagnosis (self-reported)							0.164
Yes	157	62.8	131	65.2	26	54.2
No	40	16.0	28	13.9	12	25.0
Unknown	53	21.2	42	20.9	10	20.8
Smoking status Former smoker row 70 Tested, 15 Not tested but Total = 86 diagnosis (self-reported)							0.882
Never smoker	100	40.0	79	39.3	21	43.8
Former smoker	86	34.4	70	34.8	15	31.3
Current smoker	21	8.4	18	9.0	3	6.3
Unknown	43	17.2	34	16.9	9	18.8
Family history of cancer at diagnosis (self-reported)							0.485
Yes	139	55.6	115	57.2	23	47.9
No	67	26.8	52	25.9	15	31.3
Unknown	44	17.6	34	16.9	10	20.8
WHO performance status at diagnosis							0.217
0	142	56.8	113	56.2	29	60.4
1	54	21.6	43	21.4	11	22.9
2	14	5.6	11	5.5	3	6.3
3	3	1.2	1	0.5	2	4.2
Unknown	37	14.8	33	16.4	3	6.3
Frailty at diagnosis (GFI)							0.533
<4 (non-frail)	114	45.6	91	45.3	23	47.9
≥4 (frail)	47	18.8	36	17.9	11	22.9
Unknown	89	35.6	74	36.8	14	29.2
Histology at diagnosis							<0.001
High-grade serous	173	69.2	150	74.6	22	45.8
Non-high-grade serous	72	28.8	48	23.9	24	50.0
Adenocarcinoma NOS	5	2.0	3	1.5	2	4.2
FIGO stage at diagnosis							0.018
I/II	64	25.6	45	22.4	19	39.6
III/IV	185	74.0	155	77.1	29	60.4
Unknown	1	0.4	1	0.5	–	–

One patient who rejected germline test was not included in analysis by testing status.
*Educational levels were defined as follows: low=primary or secondary education or less, medium=vocational education, high=university or higher education.
BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; GFI, Groningen Frailty Index; IQR, Interquartile range; NOS, not otherwise specified.