Patient and tumor characteristics for the entire cohort and by patient age group
| Characteristics | Entire cohort (801 patients) n (%) | Younger elderly (627 patients) n (%) | Older elderly (174 patients) n (%) | P value |
| Age, years (median, range) | 69 (65–90) | 68 (65–74) | 77 (75–90) | |
| Tumor size, cm | 4.5±2.1 | 4.4±2.1 | 4.7±2.1 | 0.13 |
| Histology | ||||
| Endometrioid | 573 (71.5) | 458 (73.0) | 115 (66.1) | 0.09 |
| Non-endometrioid | 228 (28.5) | 169 (27.0) | 59 (33.9) | |
| Grade | ||||
| 1 | 183 (22.8) | 150 (24.0) | 33 (19.0) | 0.04 |
| 2 | 272 (34.0) | 221 (35.2) | 51 (29.3) | |
| 3 | 346 (43.2) | 256 (40.8) | 90 (51.7) | |
| LVSI | ||||
| Positive | 346 (43.2) | 272 (43.4) | 74 (42.5) | 0.13 |
| Negative | 344 (42.9) | 276 (44.0) | 68 (39.1) | |
| Unknown | 111 (13.9) | 79 (12.6) | 32 (18.4) | |
| Myometrial invasion | ||||
| None | 35 (4.4) | 29 (4.6) | 6 (3.4) | 0.83 |
| <1/2 | 259 (32.3) | 204 (32.5) | 55 (31.7) | |
| ≥1/2 | 507 (63.3) | 394 (62.9) | 113 (64.9) | |
| Glandular invasion | ||||
| Positive | 126 (15.7) | 88 (14.0) | 38 (21.8) | 0.03 |
| Negative | 614 (76.7) | 492 (78.5) | 122 (70.1) | |
| Unknown | 61 (7.6) | 47 (7.5) | 14 (8.1) | |
| Stromal invasion | ||||
| Positive | 235 (29.3) | 175 (27.9) | 60 (34.5) | 0.04 |
| Negative | 566 (70.7) | 452 (72.1) | 114 (65.5) | |
| Stage | ||||
| IA | 179 (22.3) | 146 (23.4) | 33 (19.0) | 0.87 |
| IB | 275 (34.3) | 212 (33.8) | 63 (36.2) | |
| II | 118 (14.8) | 91 (14.5) | 27 (15.5) | |
| IIIA | 38 (4.7) | 29 (4.7) | 9 (5.2) | |
| IIIB | 3 (0.4) | 3 (0.5) | 0 | |
| IIIC1 | 105 (13.1) | 81 (12.9) | 24 (13.8) | |
| IIIC2 | 83 (10.4) | 65 (10.4) | 18 (10.3) | |
| Lymph node dissection | ||||
| None | 67 (8.4) | 47 (7.5) | 20 (11.5) | 0.2 |
| Pelvic LND | 227 (28.3) | 176 (28.1) | 51 (29.3) | |
| Pelvic+PA LND | 507 (63.3) | 404 (64.4) | 203 (59.2) | |
| Radiotherapy | ||||
| BRT | 362 (45.2) | 284 (45.3) | 78 (44.8) | 0.92 |
| ERT | 145 (18.1) | 113 (18.0) | 32 (18.4) | |
| ERT+BRT | 294 (36.7) | 230 (36.7) | 64 (36.8) | |
| Chemotherapy | ||||
| None | 597 (74.5) | 463 (73.8) | 134 (77.0) | 0.2 |
| Sequential | 124 (15.5) | 99 (15.8) | 25 (14.4) | |
| Sandwich | 80 (10.0) | 65 (10.4) | 15 (8.6) |
BRT, brachytherapy; ERT, external radiotherapy; LND, lymph node dissection; LVSI, lymphovascular space invasion; PA, para-aortic.