Multivariable ORs and 95% CIs for associations between mFI status and composite complications stratified by procedure type, National Surgical Quality Improvement Program, 2014–2020
| mFI status | Minor complications | Major complications | Wound complications | Any complications | ||||||||||||
| None (n=372) | Any (n=70) | None (n=400) | Any (n=42) | None (n=384) | Any (n=58) | None (n=353) | Any (n=89) | |||||||||
| n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | |
| Non-frail | 286 (76.9) | 50 (71.4) | 1.00 | 0.25 | 305 (76.3) | 31 (73.8) | 1.00 | 0.99 | 293 (76.3) | 43 (74.1) | 1.00 | 0.60 | 271 (76.8) | 65 (73.0) | 1.00 | 0.82 |
| Frail | 86 (23.1) | 20 (28.6) | 1.40 (0.79 to 2.51) | 95 (23.8) | 11 (26.2) | 0.99 (0.47 to 2.12) | 91 (23.7) | 15 (25.9) | 1.19 (0.63 to 2.25) | 82 (23.2) | 24 (27.0) | 1.07 (0.62 to 1.84) | ||||
| Radical vulvectomy+unilateral IFN | ||||||||||||||||
| None (n=134) | Any (n=39) | None (n=154) | Any (n=19) | None (n=140) | Any (n=33) | None (n=128) | Any (n=45) | |||||||||
| mFI status | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P Value | n (%) | n (%) | OR (95% CI) | P value |
| Non-frail | 104 (77.6) | 28 (71.8) | 1.00 | 0.36 | 120 (77.9) | 12 (63.2) | 1.00 | 0.38 | 109 (77.9) | 23 (69.7) | 1.00 | 0.28 | 101 (78.9) | 31 (68.9) | 1.00 | 0.29 |
| Frail | 30 (22.4) | 11 (28.2) | 1.46 (0.64 to 3.23) | 34 (22.1) | 7 (36.8) | 1.63 (0.55 to 4.82) | 31 (22.1) | 10 (30.3) | 1.61 (0.68 to 3.79) | 27 (21.1) | 14 (31.1) | 1.53 (0.69 to 3.35) | ||||
| Radical vulvectomy+bilateral IFN | ||||||||||||||||
| None (n=208) | Any (n=63) | None (n=227) | Any (n=44) | None (n=214) | Any (n=57) | None (n=191) | Any (n=80) | |||||||||
| mFI status | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value | n (%) | n (%) | OR (95% CI) | P value |
| Non-frail | 160 (76.9) | 41 (65.1) | 1.00 | 0.05 | 176 (77.5) | 25 (56.8) | 1.00 | 0.04 | 162 (75.7) | 39 (68.4) | 1.00 | 0.20 | 150 (78.5) | 51 (63.8) | 1.00 | 0.02 |
| Frail | 48 (23.1) | 22 (34.9) | 1.87 (1.00 to 3.48) | 51 (22.5) | 19 (43.2) | 2.13 (1.03 to 4.40) | 52 (24.3) | 18 (31.6) | 1.54 (0.80 to 2.96) | 41 (21.5) | 29 (36.3) | 2.10 (1.14 to 3.87) | ||||
Minor complications adjusted for: age (<65, ≥65).
Major complications adjusted for: BMI (<30, 30–40, ≥40, unknown), ASA classification (1–2, ≥3), on dialysis prior to surgery (no vs yes).
Wound complications adjusted for: age (<65, ≥65).
Any complications adjusted for: ASA classification (1–2, ≥3), on dialysis prior to surgery (no vs yes).
ASA, American Society of Anesthesiologists; BMI, body mass index; IFN, ?????; mFI, modified frailty index.