Baseline characteristics of patients according to different adjuvant treatment modalities before and after matching
| Variables | Unmatched cohort (n=192) | Matched cohort (n=75) | |||||||
| RT (n=25) | CCRT (n=40) | SCRT (n=127) | SMD | P value | RT (n=25) | CCRT (n=25) | SCRT (n=25) | SMD | |
| Age (years)* | 48±10.6 | 49±9.5 | 47±8.8 | 0.115 | 0.613 | 48±10.6 | 47±8.9 | 47±9.0 | 0.071 |
| Diameter of tumor (cm) | 0.270 | 0.439 | 0.292 | ||||||
| ≤2 | 6 | 6 | 16 | 6 | 4 | 3 | |||
| >2 to ≤4 | 13 | 25 | 69 | 13 | 17 | 16 | |||
| >4 | 6 | 9 | 42 | 6 | 4 | 6 | |||
| Tumor grade | 0.232 | 0.325 | 0.134 | ||||||
| G1-2 | 6 | 16 | 37 | 6 | 5 | 4 | |||
| G3 | 19 | 24 | 89 | 19 | 20 | 21 | |||
| Depth of stromal invasion | 0.125 | 0.744 | 0.061 | ||||||
| <1/2 | 7 | 8 | 28 | 7 | 7 | 6 | |||
| >1/2 | 18 | 32 | 99 | 18 | 18 | 19 | |||
| LVSI | 0.125 | 0.724 | 0.056 | ||||||
| No | 17 | 23 | 76 | 17 | 16 | 17 | |||
| Yes | 8 | 16 | 51 | 8 | 9 | 8 | |||
| Parametrial involvement | 0.278 | 0.237 | – | ||||||
| No | 25 | 39 | 118 | 25 | 25 | 25 | |||
| Yes | 0 | 1 | 9 | 0 | 0 | 0 | |||
| Surgical margins | 0.349 | 0.195 | – | ||||||
| Negative | 25 | 36 | 112 | 25 | 25 | 25 | |||
| Positive | 0 | 4 | 15 | 0 | 0 | 0 | |||
| Vaginal involvement | 0.391 | 0.062 | – | ||||||
| No | 25 | 38 | 110 | 25 | 25 | 25 | |||
| Yes | 0 | 2 | 17 | 0 | 0 | 0 | |||
| Common iliac LN | 0.228 | 0.232 | 0.146 | ||||||
| Negative | 21 | 37 | 103 | 21 | 22 | 20 | |||
| Positive | 4 | 3 | 24 | 4 | 3 | 5 | |||
| Number of positive LN | 0.074 | 0.908 | 0.108 | ||||||
| 1 | 12 | 17 | 56 | 12 | 10 | 10 | |||
| ≥2 | 13 | 23 | 71 | 13 | 15 | 15 | |||
*Value is mean (±SD).
CCRT, concurrent chemoradiation; LN, lymph node; LVSI, lymphovascular space invasion; RT, radiotherapy; SCRT, sequential chemoradiation; SMD, standardized mean difference.