Major characteristics of studies included in the systematic review
| Author/year | Accrual time | Study type | N total | N early (I-IIA) low-grade serous | Age (years) | FIGO stage clinically presumed | Histologic subtype grade | Procedure/fertility-preserving | Procedure/primary vs re-staging |
| Bogani 201713 | 1975–2016 | Retrospective | 290 | 37 | 49.8 (18.1–76) median | I-II (85.9%, 14.1%) | Low-grade | Hysterectomy, bilateral salpingo-oophorectomy, peritoneal random peritoneal biopsies; omentectomy | Both |
| Minig 201714 | 2000–2016 | Retrospective | 163 | 56 | 50 median (18–81) whole cohort | I | Low-grade | Bilateral salpingo-oophorectomy (97.5%), hysterectomy (82.8%), omentectomy (98.8%), and appendectomy (68.1%) | Both |
| Heitz 201816 | 2000–2016 | Retrospective | 762 | 5 | 57 median (18–82) whole cohort | pT1a-pT2aM0 (I-II) | Grade 1 | Staging surgery | Primary |
| Nasioudis 201820 | 1988–2014 | Population-based SEER | 1242 | 67 | 51 median | IA, IB, IC | Grade 1 | NR | NR |
| Wafa 201918 | 2000–2017 | Retrospective | 37 | 4 | 48 (26–76) whole cohort | pT1a-pT2aM0 (I-II) | Low-grade | Primary surgery | Primary |
| Simon 202015 | 2000–2017 | Retrospective | 126 | 11 | 53 median (19–82) | I-II | Low-grade | NR | Primary |
| Chen 202117 | 2005–2015 | Retrospective | 196 | 37 | NR as median or average | I-IIA | Low-grade | NR | NR |
| Durmuş 202219 | 1999–2018 | Retrospective | 148 | 60 | 49.1 mean (21–84) | I | Grade 1/low-grade | Both (complete surgery consisted of total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and peritoneal biopsies) | Primary |
| Total | 2964 | 277 |
FIGO, International Federation of Gynecology and Obstetrics; NR, not reported; SEER, Surveillance, Epidemiology, and End Results Program.