Table 1

Clinico-pathological characteristics based on receipt of adjuvant chemotherapy

Variable
EBRTP valueVBTP valueTotalP value
No chemotherapy (n=693)Chemotherapy
(n=130)
No chemotherapy
(n=1724)
Chemotherapy
(n=334)
No chemotherapy
(n=2417)
Chemotherapy
(n=464)
Age
 <65
>65
341 (49.2%)
352 (50.8%)
73 (56.2%)
57 (43.8%)
0.15781 (45.3%)
943 (54.7%)
209 (62.6%)
125 (37.4%)
<0.001 1122 (46.4%)
1295 (53.6%)
282 (60.8%)
182 (39.2%)
<0.001
Race
 White
 Black
 Other/unknown
601 (86.7%)
60 (8.7%)
32 (4.6%)
110 (84.6%)
11 (8.5%)
n<10
0.541545 (89.6%)
98 (5.7%)
81 (4.7%)
301 (90.1%)
18 (5.4%)
15 (4.5%)
0.962146 (88.8%)
158 (6.5%)
113 (4.7%)
411 (88.6%)
29 (6.3%)
24 (5.2%)
0.88
Comorbidities
 No
 Yes
514 (74.2%)
179 (25.8%)
97 (74.6%)
33 (25.4%)
0.921271 (73.7%)
453 (26.3%)
262 (78.4%)
72 (21.6%)
0.071785 (73.9%)
632 (26.1%)
359 (77.4%)
105 (22.6%)
0.11
Insurance
 Private
 Government
 Uninsured/unknown
303 (43.7%)
365 (52.7%)
25 (3.6%)
67 (51.5%)
57 (43.8%)
n<10
0.18756 (43.8%)
917 (53.2%)
51 (3%)
194 (58.1%)
122 (36.5%)
18 (5.4%)
<0.001 1059 (43.8%)
1282 (53%)
76 (3.2%)
261 (56.3%)
179 (38.6%)
24 (5.1%)
<0.001
Reporting facility*
 Academic
 Non-academic
245 (35.5%)
445 (64.5%)
52 (40.6%)
76 (59.4%)
0.27893 (52%)
824 (48%)
174 (52.4%)
158 (47.6%)
0.891138 (47.3%)
1269 (52.7%)
226 (49.1%)
234 (50.9%)
0.47
Tumor grade
 Grade 1
 Grade 2
 Grade 3
95 (13.7%)
291 (42%)
307 (44.3%)
11 (8.5%)
29 (22.3%)
90 (69.2%)
<0.001 388 (22.5%)
941 (54.6%)
395 (22.9%)
33 (9.9%)
107 (32%)
194 (58.1%)
<0.001 483 (20%)
1232 (51%)
702 (29%)
44 (9.5%)
136 (29.3%)
284 (61.2%)
<0.001
Myometrial invasion
 IA
 IB
 INOS
129 (18.6%)
559 (80.7%)
n<10
19 (14.6%)
111 (85.4%)
0.33628 (36.4%)
1082 (62.8%)
14 (0.8%)
90 (26.9%)
237 (71%)
n<10
<0.001 757 (31.3%)
1641 (67.9%)
19 (0.8%)
109 (23.5%)
348 (75%)
n<10
0.001
LN removed
 1–9
 10–20
 >20
292 (42.1%)
257 (37.1%)
144 (20.8%)
44 (33.8%)
43 (33.1%)
43 (33.1%)
0.008 494 (28.7%)
753 (43.7%)
477 (27.3%)
80 (24%)
135 (40.4%)
119 (35.6%)
0.011 786 (32.5%)
1010 (41.8%)
621 (25.7%)
124 (26.7%)
178 (38.4%)
162 (34.9%)
<0.001
Tumor size
 <2 cm
 2–4 cm
 >4 cm
 Not reported
35 (5.1%)
212 (30.6%)
372 (53.7%)
74 (10.6%)
n<10
32 (24.6%)
80 (61.5%)
14 (10.8%)
0.3299 (5.7%)
539 (31.3%)
836 (48.5%)
250 (14.5%)
11 (3.3%)
100 (29.9%)
185 (55.4%)
38 (11.4%)
0.047 134 (5.5%)
751 (31.1%)
1208 (50%)
324 (13.4%)
15 (3.2%)
132 (28.4%)
265 (57.1%)
52 (11.3%)
0.017
  • Bold values indicate p<0.05.

  • *Not available for patients aged <45 years per National Cancer Database.

  • EBRT, external beam radiation therapy; VBT, vaginal brachytherapy.