Table 4

Desensitization outcomes

Characteristicn=186
Median time in chemo unit, minutes (range)380 (325–630)
Median number of desensitization cycles, n (range)3 (1–28)
Successful completion of ≥3 cycles, n (%)104 (56%)
Breakthrough HSR during desensitization, n (%)79 (42%)
Reason for drug discontinuation, n (%)
 Progression of disease84 (45%)
 Hypersensitivity reaction*41 (22%)
 End of treatment38 (20%)
 Other13 (7%)
 Ongoing10 (5%)
 Drugs discontinued due to breakthrough HSR (n=41)*
  Oxaliplatin20 (49%)
  Carboplatin14 (34%)
  Cisplatin2 (5%)
  Paclitaxel2 (5%)
  Trastuzumab2 (5%)
  Liposomal doxorubicin1 (2%)
  • HSR, hypersensitivity reaction.