Characteristic | n=186 |
Median time in chemo unit, minutes (range) | 380 (325–630) |
Median number of desensitization cycles, n (range) | 3 (1–28) |
Successful completion of ≥3 cycles, n (%) | 104 (56%) |
Breakthrough HSR during desensitization, n (%) | 79 (42%) |
Reason for drug discontinuation, n (%) | |
Progression of disease | 84 (45%) |
Hypersensitivity reaction* | 41 (22%) |
End of treatment | 38 (20%) |
Other | 13 (7%) |
Ongoing | 10 (5%) |
Drugs discontinued due to breakthrough HSR (n=41)* | |
Oxaliplatin | 20 (49%) |
Carboplatin | 14 (34%) |
Cisplatin | 2 (5%) |
Paclitaxel | 2 (5%) |
Trastuzumab | 2 (5%) |
Liposomal doxorubicin | 1 (2%) |
HSR, hypersensitivity reaction.