Challenges to effective radiotherapy treatment of locally advanced cervical cancer not discussed in this review
| Facility-related barriers | Significant time required to plan teletherapy treatments |
| Cost and logistics of replacing cobalt brachytherapy units in low- and middle-income countries | |
| Patient-related barriers | Cost of treatment, including monetary cost directly to the patient and additional unseen costs of supportive care, transportation, and childcare |
| Compliance with chemoradiation regimen, including issues with distance to treatment facility |