Table 1

Challenges to effective radiotherapy treatment of locally advanced cervical cancer not discussed in this review

Facility-related barriersSignificant time required to plan teletherapy treatments
Cost and logistics of replacing cobalt brachytherapy units in low- and middle-income countries
Patient-related barriersCost of treatment, including monetary cost directly to the patient and additional unseen costs of supportive care, transportation, and childcare
Compliance with chemoradiation regimen, including issues with distance to treatment facility