Table 3

Adjusted hazard ratios for employment change among patients with gynecologic cancer

CharacteristicsHR (95% CI)P value
Age at diagnosis, years
44 or less1.00 (Reference)
45 to 490.99 (0.82 to 1.18)0.9
50 to 530.85 (0.71 to 1.03)0.1
54 to 571.14 (0.97 to 1.34)0.1
58 to 631.32 (1.14 to 1.54)0.0003
Health insurance plan type
HMO1.00 (Reference)
PPO1.09 (0.94 to 1.27)0.2
Other*1.38 (1.17 to 1.63)0.0001
Region
Northeast1.00 (Reference)
North central1.17 (1.01 to 1.37)0.04
South0.76 (0.65 to 0.87)0.0002
West1.25 (1.06 to 1.47)0.0064
Unknown0.68 (0.10 to 4.80)0.7
Charlson Comorbidity Index score
01.00 (Reference)
1+1.21 (1.05 to 1.41)0.01
Cancer type
Endometrial1.00 (Reference)
Cervical0.96 (0.81 to 1.15)0.7
Ovarian0.87 (0.77 to 0.99)0.04
Vulvar0.76 (0.53 to 1.10)0.1
Treatment group
Surgery only1.00 (Reference)
Surgery with adjuvant treatment1.35 (1.20 to 1.52)<0.0001
Chemotherapy, radiation, or chemoradiation only1.39 (1.10 to 1.76)0.006
Adverse events
None1.00 (Reference)
11.05 (0.91 to 1.20)0.5
2+1.00 (0.71 to 1.41)0.9
Year of diagnosis
20091.00 (Reference)
20100.90 (0.71 to 1.15)0.4
20110.98 (0.77 to 1.23)0.8
20120.85 (0.67 to 1.08)0.2
20130.98 (0.77 to 1.24)0.9
20140.79 (0.62 to 1.02)0.06
20151.00 (0.80 to 1.24)0.9
20161.05 (0.85 to 1.30)0.6
20170.99 (0.80 to 1.24)0.9
  • *Other health insurance plans include comprehensive, point-of-service, point-of-service with capitation, high-deductible, and exclusive-provider-organization health plans.

  • HMO, health maintenance organization; PPO, preferred provider organization.