Table 2

Characteristics of patients with gynecologic cancer diagnosed between 2009 and 2017 and female controls, before and after propensity-score matching

CharacteristicBefore matchingPropensity score-matched cohort
Cases
(n=7446)
Controls
(n=3 196 347)
P*Cases
(n=7294)
Controls
(n=28 019)
P*
Age at cohort entry, median (IQR)† 53 (46–58)46 (36–54)<0.000153 (46–58)53 (46–58)0.2
Age at cohort entry by group, n (%)† <0.0010.8
44 or less1613 (21.7)1 504 223 (47.0)1597 (21.9)6263 (22.4)
45 to 491038 (13.9)459 818 (14.4)1023 (14.0)3986 (14.2)
50 to 531176 (15.8)377 048 (11.8)1155 (15.8)4468 (15.9)
54 to 571611 (21.6)382 509 (12.0)1567 (21.5)5940 (21.2)
58 to 632008 (27.0)472 749 (14.8)1952 (26.8)7362 (26.3)
Health insurance plan type, n (%) 0.30.1
HMO1130 (15.2)481 569 (15.1)1070 (14.7)3867 (13.8)
PPO4158 (55.8)1 763 576 (55.2)4116 (56.4)16 046 (57.3)
Other‡2158 (29.0)951 202 (29.8)2108 (28.9)8106 (28.9)
Region, n (%) <0.0010.6
Northeast1290 (17.3)484 037 (15.1)1249 (17.1)4717 (16.8)
North central1660 (22.3)649 676 (20.3)1615 (22.1)6131 (21.9)
South3056 (41.0)1 395 390 (43.7)3037 (41.6)11 916 (42.5)
West1432 (19.2)661 986 (20.7)1392 (19.1)5254 (18.8)
Unknown8 (0.1)5258 (0.2)1 (0.0)1 (0.0)
Charlson Comorbidity Index score, n (%) <0.001<0.001
06512 (87.5)2 981 805 (93.3)6485 (88.9)25 542 (91.2)
1+934 (12.5)214 542 (6.7)809 (11.1)2477 (8.8)
Index date year, n (%) <0.001<0.001
2009629 (8.4)312 039 (9.8)620 (8.5)2041 (7.3)
2010681 (9.1)316 182 (9.9)672 (9.2)2541 (9.1)
2011729 (9.8)339 851 (10.6)709 (9.7)2676 (9.6)
2012762 (10.2)352 848 (11.0)739 (10.1)2809 (10.0)
2013705 (9.5)276 864 (8.7)687 (9.4)2672 (9.5)
2014689 (9.3)277 150 (8.7)669 (9.2)2500 (8.9)
2015899 (12.1)348 106 (10.9)871 (11.9)3032 (10.8)
20161216 (16.3)464 009 (14.5)1198 (16.4)4629 (16.5)
20171136 (15.3)509 298 (15.9)1129 (15.5)5119 (18.3)
  • Propensity-score matching based on all tabulated characteristics.

  • *P values derived from the Pearson χ2 test or Wilcoxon rank-sum test.

  • †Age at diagnosis for cancer cohort and age at index date (date of billable encounter with provider) for control cohort.

  • ‡Other health insurance plans include comprehensive, point-of-service, point-of-service with capitation, high-deductible, and exclusive-provider-organization health plans.

  • HMO, health maintenance organization; PPO, preferred provider organization.