Characteristics of the women
|
Age | 44.75 (8.95) | 45.33 (10.34) | 0.731 |
BMI | 24.92 (4.85) | 24.71 (4.35) | 0.816 |
Performance status | | | 0.037 |
ECOG O | 28 (87.5) | 355 (90.8) | |
ECOG 1 | 3 (9.4) | 10 (2.6) | |
Not reported | 1 (3.1) | 26 (6.6) | |
Smoker | | | 0.266 |
Yes | 24 (75.0) | 228 (58.3) | |
No | 4 (12.5) | 70 (17.9) | |
Not reported | 4 (12.5) | 93 (23.8) | |
Characteristics of the tumor
|
Volume of the tumor | 3427.28 (6904.14) | 1747.19 (5681.87) | 0.189 |
Clinical size of the tumor | | | 0.343 |
<30mm | 22 (68.8) | 306 (78.3) | |
≥30mm | 8 (25.0) | 74 (18.9) | |
Not reported | 2 (6.2) | 11 (2.8) | |
Diameter of the tumor | | | 0.006 |
≤20mm | 21 (65.6) | 329 (84.1) | |
>20mm | 11 (34.4) | 60 (15.3) | |
Not reported | 0 (0.0) | 2 (0.5) | |
Histology of the tumor | | | 0.555 |
Squamous carcinoma | 1 (3.1) | 18 (4.6) | |
Adenocarcinoma | 23 (71.9) | 244 (62.4) | |
Adenosquamous carcinoma | 5 (15.6) | 101 (25.8) | |
Related to the conization proceedure
|
Tumor volume | 1489.49 (2188.48) | 1378.20 (3898.83) | 0.799 |
Dimension of tumor in cone | 15.68 (6.82) | 14.49 (6.87) | 0.347 |
MRI done before cone | | | 0.990 |
Yes | 23 (71.9) | 288 (73.7) | |
No | 5 (15.6) | 63 (16.1) | |
Not reported | 4 (12.5) | 40 (10.2) | |
Type of cone technique | | | 0.345 |
Cold knife | 3 (9.4) | 73 (18.7) | |
Laser | 1 (3.1) | 21 (5.4) | |
LEEP or LLETZ | 25 (78.1) | 268 (68.5) | |
Margins in the cone | | | 0.033 |
Not affected | 2 (6.2) | 87 (22.3) | |
Uncertain | 0 (0.0) | 14 (3.6) | |
Afected | 28 (87.5) | 253 (64.7) | |
Linfovascular invasion in the cone | | | 0.681 |
Yes | 8 (25.0) | 90 (23.0) | |
No | 5 (15.6) | 44 (11.3) | |
Not reported | 19 (59.4) | 257 (65.7) | |
Tumor grade of differentiation in cone | | | 0.963 |
Grade I | 7 (21.9) | 74 (18.9) | |
Grade II | 13 (40.6) | 130 (33.2) | |
Grade III | 7 (21.9) | 80 (20.5) | |
Tumor histology in the cone | | | 0.010 |
Squamous carcinoma | 25 (78.1) | 256 (65.5) | |
Adenocarcinoma | 5 (15.6) | 109 (27.9) | |
Adenosquamous carcinoma | 2 (6.2) | 3 (0.8) | |
Depth of invasion the cone | | | 0.002 |
Superficially invades stroma | 1 (3.1) | 81 (20.7) | |
Invades 1/3 of stroma | 2 (6.2) | 51 (13.0) | |
Invades 2/3 of stroma | 13 (40.6) | 76 (19.4) | |
Endocervical curettage carried out | | | 0.471 |
Yes | 24 (75.0) | 249 (63.7) | |
No | 7 (21.9) | 100 (25.6) | |
Not reported | 1 (3.1) | 42 (10.7) | |
Positive endocervical curretage | | | 0.499 |
Yes | 3 (9.4) | 56 (14.3) | |
No | 4 (12.5) | 44 (11.3) | |
Not reported | 25 (78.1) | 291 (74.4) | |
Disease free survival | 51.69 (21.64) | 51.52 (19.47) | 0.967 |
Overall survival | 51.88 (21.37) | 52.79 (18.45) | 0.815 |