Comparison of characteristics of the two groups.
| Variable | Open, N=48 (%, range) | MIPE, N=35 (%, range) | p-value |
|---|---|---|---|
| Median age, years | 49 (29-84) | 63 (38-82) | 0.009 |
| Median BMI, kg/m2 | 24 (13.8-39.5) | 26 (18.8-53.9) | 0.041 |
| Time from diagnosis to pelvic exenteration, months | 15 (4-282) | 29 (1-288) | 0.157 |
|
Primary site of disease
Cervical cancer Endometrial cancer Vaginal cancer Vulvar Urothelial cancer | 39 (81.3) 6 (12.5) 2 (4.2) 0 1 (2.1) | 17 (48.6) 12 (34.3) 4 (11.4) 1 (2.9) 1 (2.9) | 0.032 |
|
Grading
G1 G2 G3 Unknown | 4 (8.3) 19 (39.6) 9 (18.7) 16 (33.3) | 4 (11.4) 14 (40.0) 14 (40.0) 3 (8.6) | 0.398 |
|
Previous treatment
None Chemotherapy Radio(chemo)therapy | 1 (2.1) 5 (10.4) 42 (87.5) | 6 (17.1) 4 (11.4) 25 (71.4) | 0.047 |
|
Type of exenteration
Anterior Total | 33 (68.8) 15 (31.3) | 26 (74.3) 9 (25.7) | 0.631 |
|
Resection Margins
Microscopically negative (R0) Microscopically positive (R1) Grossly positive (R2) | 41 (85.4) 6 (12.5) 1 (2.1) | 27 (77.1) 7 (20.0) 1 (2.9) | 0.623 |
| Maximum tumor diameter, mm** | 35 (2-50) | 35 (1-120) | 0.273 |
| Metastatic pelvic lymph nodes | 5 (10.4) | 4 (11.4) | 0.884 |
| Adjuvant chemotherapy | 24 (51.1) | 25 (44.1) | 0.653 |