Abstract 746 Table 1
Before IPWAfter IPW
Was centinel node biopsy performed? p-value Was centinel node biopsy performed? p-value
Variable name Yes No Yes No
Characteristics of the women
Age 46.57 (10.56) 47.25 (10.98) 0.395 45.86 (10.07) 46.91 (11.05) 0.348
BMI 24.93 (4.57) 25.43 (4.27) 0.139 24.89 (4.09) 25.39 (4.28) 0.265
Performance status 0.852 0.689
ECOG O 205 (91.5) 774 (90.1) 205 (90.6) 774 (90.5)
ECOG 1 14 (6.2) 56 (6.5) 14 (7.0) 56 (6.1)
Not reported 5 (2.2) 29 (3.4) 5 (2.4) 29 (3.4)
Smoker 0.886 0.003
Yes 147 (65.6) 476 (55.4) 147 (60.5) 476 (55.5)
No 49 (21.9) 163 (19.0) 49 (22.0) 163 (19.2)
Not reported 28 (12.5) 220 (25.6) 28 (17.5) 220 (25.3)
Characteristics of the tumor
Volume of the tumor 7416.52 (9594.55) 8029.76 (11650.87) 0.417 9015.10 (11055.48) 7714.04 (11305.59) 0.445
Maximum diameter 0.163 0.689
≤20mm 136 (60.7) 477 (55.5) 136 (56.5) 477 (56.3)
>20mm 88 (39.3) 382 (44.5) 88 (43.5) 382 (43.7)
Linfovascular space invasion 0.682 0.064
Yes 125 (55.8) 464 (54.0) 125 (50.5) 464 (55.0)
No 82 (36.6) 285 (33.2) 82 (41.8) 285 (32.7)
Not reported 17 (7.6) 110 (12.8) 17 (7.7) 110 (12.3)
Parametrial space invasion 0.071 0.284
Yes 221 (98.7) 823 (95.8) 221 (97.3) 823 (96.4)
No 2 (0.9) 26 (3.0) 2 (2.2) 26 (2.6)
Not reported 1 (0.4) 10 (1.2) 1 (0.6) 10 (1.0)
Vaginal invasion 0.770 0.543
Yes 216 (96.4) 821 (95.6) 216 (94.1) 821 (95.8)
No 5 (2.2) 22 (2.6) 5 (3.3) 22 (2.5)
Not reported 3 (1.3) 16 (1.9) 3 (2.6) 16 (1.7)
Uterine invasion 0.954 0.397
Yes 203 (90.6) 785 (91.4) 203 (88.2) 785 (91.6)
No 15 (6.7) 57 (6.6) 15 (8.3) 57 (6.3)
Not reported 6 (2.7) 17 (2.0) 6 (3.5) 17 (2.1)
Margins on the final specimen 0.424 0.257
Free 212 (94.6) 800 (93.1) 212 (94.1) 800 (93.4)
Free but close (<2mm) or positive 8 (3.6) 49 (5.7) 8 (2.7) 49 (5.5)
Not reported 3 (1.3) 9 (1.0) 3 (2.5) 9 (1.0)
Macroscopic appearance 0.111 0.595
Exophytic 100 (44.6) 365 (42.5) 100 (45.7) 365 (43.0)
Endophytic ulcerative 34 (15.2) 182 (21.2) 34 (14.3) 182 (21.0)
Endophytic barrel-shaped 22 (9.8) 66 (7.7) 22 (8.5) 66 (7.4)
Histology of the tumor 0.514 0.231
Squamous carcinoma 153 (68.3) 588 (68.5) 153 (71.9) 588 (68.1)
Adenocarcinoma 66 (29.5) 239 (27.8) 66 (26.0) 239 (28.3)
Adenosquamous carcinoma 5 (2.2) 32 (3.7) 5 (2.1) 32 (3.5)
Tumor grade of differentiation 0.355 0.456
Grade I 32 (14.3) 132 (15.4) 32 (13.3) 132 (15.8)
Grade II 89 (39.7) 372 (43.3) 89 (46.4) 372 (43.4)
Grade III 73 (32.6) 239 (27.8) 73 (28.5) 239 (28.0)
Characteristics of the proceedure
Uterine manipulator used 0.000 0.000
Yes 91 (40.6) 631 (73.5) 91 (67.0) 631 (66.7)
No 94 (42.0) 149 (17.3) 94 (22.3) 149 (22.4)
Not reported 39 (17.4) 79 (9.2) 39 (10.8) 79 (10.9)
Surgical approach 0.000 0.933
Laparoscopic or robotic 162 (72.3) 325 (37.8) 162 (45.4) 325 (44.9)
Open 62 (27.7) 534 (62.2) 62 (54.6) 534 (55.1)
Surgical experience of surgeon in charge 0.000 0.783
Fellow in gyn oncology 3 (1.3) 44 (5.1) 3 (3.8) 44 (4.4)
Junion surgeon in gyn oncology 66 (29.5) 135 (15.7) 66 (19.7) 135 (18.7)
Senior surgeon in gyn oncology 155 (69.2) 680 (79.2) 155 (76.5) 680 (76.9)
Type of radical hysterectomy performed 0.763 0.959
Modified radical hysterectomy 63 (28.1) 255 (29.7) 63 (24.5) 255 (30.7)
Classical radical hysterectomy 151 (67.4) 581 (67.6) 151 (73.5) 581 (66.4)