Baseline characteristics | n=1156 |
Age, years (SD) | 47.1 (10.8) |
Race (%) | |
Caucasian | 962 (83.2) |
Asian | 35 (3.0) |
Latin-American | 18 (1.6) |
African | 6 (0.5) |
Other | 69 (6.0) |
Not reported | 66 (5.7) |
Body mass index kg/m2 (SD) | 25.44 (4.9) |
Performance status ECOG (%) | |
PS 0 | 1022 (88.4) |
PS 1 | 78 (6.7) |
Not reported | 56 (4.8) |
Tumor clinical size, mm (SD) | 19.58 (11.4) |
<20 mm (%) | 667 (57.7) |
>20 mm (%) | 473 (40.9) |
Not reported (%) | 16 (1.4) |
Previous cone biopsy (%) | |
No | 733 (63.4) |
Yes | 423 (36.6) |
Pre-operative max diameter MRI mm (SD) | 19.58 (12.6) |
Pre-operative max diameter US,mm (SD) | 17.66 (13.3) |
Surgical procedure | n=1156 |
Surgical approach (%) | |
Open | 633 (54.8) |
Laparoscopic | 377 (32.6) |
Robotic | 139 (12.0) |
Vaginal-assisted laparoscopic | 7 (0.6) |
Type of radical hysterectomy (%) | |
Type II | 330 (28.5) |
Type III | 789 (68.3) |
Type II on one side and III on the other | 37 (3.2) |
Uterine manipulator (%) | |
No | 754 (65.2) |
Yes | 252 (21.8) |
Not reported | 150 (13.0) |
Vaginal protective maneuver (%) | |
No | 713 (61.7) |
Yes | 443 (38.3) |
Nerve-sparing technique (%) | |
No | 345 (29.8) |
Yes | 558 (48.3) |
Not reported | 253 (21.9) |
Nodal assessment (%) | |
Bilateral pelvic lymphadenectomy | 910 (78.7) |
Pelvic and para-aortic lymphadenectomy | 22 (2.3) |
SLNB and bilateral pelvic lymphadenectomy | 224 (19.4) |
Sentinel lymph node biopsy (%) | |
No | 872 (75.4) |
Yes | 224 (19.4) |
Not reported | 60 (5.2) |
SLNB tracer (%) | |
Blue dye and technetium | 95 (42.4) |
Blue dye alone | 61 (27.2) |
Technetium alone | 24 (10.7) |
Indocyanine green | 14 (6.3) |
Technetium and indocyanine green | 5 (2.2) |
Not reported | 25 (11.2) |
SLNB Identification (%) | |
Bilateral | 182 (81.3) |
Unilateral | 22 (9.8) |
None | 20 (8.9) |
Duration of procedure, min (SD) | 217.4 (75.0) |
Estimated blood loss, cc (SD) | 317.5 (170.6) |
Length of stay, days (SD) | 6.7 (4.2) |
Complications | |
Intra-operative complications (%) | |
No | 1012 (87.5) |
Yes | 108 (9.3) |
Not reported | 36 (3.1) |
Type of complication (%) | |
Bleeding | 83 (7.2) |
Ureteral injury | 32 (2.8) |
Bladder injury | 47 (4.1) |
Bowel injury | 22 (1.9) |
Vascular injury | 35 (3.0) |
Nerve injury | 22 (1.9) |
Other | 18 (1.6) |
Post-operative complications, 30-day (%) | |
No | 875 (75.7) |
Yes | 249 (21.5) |
Not reported | 32 (2.8) |
PS, performance status; SLNB, sentinel lymph node biopsy; US, ultrasound.