Demographic and disease characteristics by financial toxicity level
| Characteristic | All respondents n=308 | Severe financial toxicity (COST 0–13) n=46 | Moderate financial toxicity (COST 14–25) n=99 | No/mild financial toxicity (COST ≥26) n=163 | P value |
| Location | 0.17 | ||||
| BIDMC | 187 (61) | 26 (57) | 54 (55) | 107 (66) | |
| UAB | 121 (39) | 20 (43) | 45 (45) | 56 (34) | |
| COST score | 26 (19–34) | 9 (6–11) | 21 (18–23) | 33 (30–38) | <0.001 |
| Age | 61 (52–69) | 54 (50–61) | 60 (49–68) | 63 (56–70) | <0.001 |
| Race/ethnicity | |||||
| White/Caucasian | 244 (79) | 30 (65) | 73 (74) | 141 (87) | 0.003 |
| Black/African American | 43 (14) | 8 (17) | 20 (20) | 15 (9) | |
| Hispanic/Latina/ Spanish | 7 (2) | 4 (9) | 2 (2) | 1 (1) | |
| Other/missing | 14 (5) | 4 (9) | 4 (4) | 6 (4) | |
| Partnership status | |||||
| Married or partnered | 180 (58) | 23 (50) | 52 (53) | 105 (64) | 0.15 |
| Single, divorced, or widowed | 126 (41) | 23 (50) | 46 (46) | 57 (35) | |
| Missing | 2 (1) | 0 (0) | 1 (1) | 1 (1) | |
| Education level | |||||
| High school or less | 54 (18) | 10 (22) | 25 (25) | 19 (12) | 0.03 |
| Completed some college | 67 (22) | 10 (22) | 26 (26) | 31 (19) | |
| Bachelor’s degree or more | 157 (51) | 22 (48) | 38 (38) | 97 (60) | |
| Missing | 30 (10) | 4 (9) | 10 (10) | 16 (10) | |
| Employment | |||||
| Employed | 119 (39) | 21 (46) | 30 (30) | 68 (42) | <0.001 |
| Not employed | 45 (15) | 13 (28) | 19 (19) | 13 (8) | |
| Retired | 130 (42) | 7 (15) | 45 (45) | 78 (48) | |
| Missing | 14 (5) | 5 (11) | 5 (5) | 4 (2) | |
| Health insurance | |||||
| Private | 150 (49) | 21 (46) | 41 (41) | 88 (54) | <0.001 |
| Medicare with supplement | 83 (27) | 4 (9) | 23 (23) | 56 (34) | |
| Medicare without supplement/military* | 35 (11) | 6 (13) | 14 (14) | 15 (9) | |
| Medicaid | 31 (10) | 9 (20) | 19 (19) | 3 (2) | |
| Uninsured | 9 (3) | 6 (13) | 2 (2) | 1 (1) | |
| Household income ($) | 62.5K (30K–100K) | 37.5K (20K–62.5K) | 37.5K (30K–70K) | 87.5K (50K–100K) | <0.001 |
| Diagnosis | |||||
| Ovarian | 146 (47) | 22 (48) | 46 (46) | 78 (48) | 0.24 |
| Uterine | 113 (37) | 13 (28) | 34 (34) | 66 (40) | |
| Cervical | 40 (13) | 10 (22) | 16 (16) | 14 (9) | |
| Vulvar/vaginal | 9 (3) | 1 (2) | 3 (3) | 5 (3) | |
| Months since diagnosis | 19 (6–47) | 11 (4–38) | 17 (4–41) | 26 (8–55) | 0.046 |
| Treatment† | |||||
| Surgery | 266 (86) | 36 (78) | 81 (82) | 149 (91) | 0.02 |
| Radiation | 68 (22) | 12 (26) | 26 (26) | 30 (18) | 0.26 |
| Systemic treatment | 206 (67) | 37 (80) | 78 (79) | 91 (56) | <0.001 |
| Hormonal treatment | 7 (2) | 0 (0) | 5 (5) | 2 (1) | 0.11 |
Data are shown as median (IQR) or number (%).
*Two respondents had military insurance.
†Treatment categories are not mutually exclusive.
BIDMC, Beth Israel Deaconess Medical Center; COST, Comprehensive Score for Financial Toxicity; K, 1000; UAB, University of Alabama at Birmingham.