Clinicopathological characteristics of patients with lymph node positive endometrial carcinoma who underwent minimally invasive hysterectomy and systematic lymphadenectomy or sentinel lymph node biopsy only
| LND (n=1323) (n (%)) | SLNBx only (n=109) (n (%)) | P value | |
| Age (years) | 0.008 | ||
| <65 | 733 (55.4) | 46 (42.2) | |
| ≥65 | 590 (44.6) | 63 (57.8) | |
| Race | 0.77 | ||
| White | 1115 (84.3) | 93 (85.3) | |
| Other/unknown | 208 (15.7) | 16 (14.7) | |
| Comorbidities | 0.15 | ||
| No | 1000 (75.6) | 89 (81.7) | |
| Yes | 323 (24.4) | 20 (18.3) | |
| Insurance | 0.17 | ||
| Private | 647 (48.9) | 53 (48.6) | |
| Government | 615 (46.5) | 55 (50.5) | |
| Uninsured/unknown | 61 (4.6) | * | |
| Reporting facility | <0.001 | ||
| Academic | 652 (49.9) | 79 (74.5) | |
| Non-academic | 655 (50.1) | 27 (25.5) | |
| Histology | 0.15 | ||
| Endometrioid | 785 (59.3) | 75 (68.8) | |
| Serous/clear cell/carcinosarcoma | 317 (24) | 19 (17.4) | |
| Mixed/other | 221 (16.7) | 15 (13.8) | |
| Approach | 0.13 | ||
| Laparoscopic | 288 (21.8) | 17 (15.6) | |
| Robotic assisted | 1035 (78.2) | 92 (84.4) | |
| Lymph–vascular invasion | 0.95 | ||
| Present | 840 (68.2) | 74 (68.5) | |
| Absent | 391 (31.8) | 34 (31.5) | |
| Tumor size (cm) | 0.06 | ||
| <2 | 85 (7.1) | * | |
| 2–4 | 330 (27.5) | 25 (39.7) | |
| ≥4 | 785 (65.4) | 32 (50.8) | |
| Adjuvant therapy† | <0.001 | ||
| None | 145 (13.4) | 16 (16.5) | |
| Radiation therapy only | 51 (4.7) | 16 (16.5) | |
| Chemotherapy only | 343 (31.7) | 11 (11.3) | |
| Chemoradiation | 543 (50.2) | 54 (55.7) | |
| No of positive lymph nodes | <0.001 | ||
| 1 | 529 (40) | 72 (66.1) | |
| 2 | 238 (18) | 19 (17.4) | |
| ≥3 | 556 (42) | 18 (16.7) |
Missing values: type of treatment facility, 19 cases; tumor size, 169 cases; lymph-vascular invasion, 93 cases.
*Suppressed, n<10 per agreement with National Cancer Database.
†Adjuvant treatment: excluded 253 cases (187 patients received chemotherapy >6 months after surgery, 63 had an unknown surgery–chemotherapy/radiotherapy interval, and 3 patients received radiation therapy >6 months after surgery).
LND, lymphadenectomy; SLNBx, sentinel lymph node biopsy.