Overview of literature on fertility and reproductive outcomes after hydatidiform mole
| Reference | HM | Women with pregnancy wish | Pregnant women | Total of pregnancies | Outcome of pregnancies | |||||||
| n | n | n | Miscarriage | TOP | Ectopic | Live birth | Preterm birth | Stillbirth | Cong abn | Repeat mole | ||
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||
| Kim et al16 | HM | ND | ND | 77 | 8 (10.4) | ND | 2 (2.6) | 64 (83.1) | 0 (0) | 1 (1.3) | 2 (2.6) | 2 (2.6) |
| CHM | ||||||||||||
| PHM | ||||||||||||
| Matsui et al17 | HM | 891 | ND | 650 | 84 (12.9) | 54 (8.3) | ND | 489 (75.2) | 11 (1.7) | 3 (0.5) | 7 (1.1) | 9 (1.4) |
| CHM | 453 | 56 (12.4) | 41 (9.1) | ND | 344 (75.9) | 4 (0.9) | 2 (0.4) | ND | 6 (1.3) | |||
| PHM | 197 | 28 (14.2) | 13 (6.6) | ND | 145 (73.6) | 7 (3.6) | 1 (0.5) | ND | 3 (1.5) | |||
| Sebire et al18 | HM | 2578 | ND | 1417 | 240 (16.9) | 64 (4.5) | 5 (0.4) | 1076 (75.9) | ND | 5 (0.4) | ND | 27 (1.9) |
| CHM | 2627 | ND | 1512 | 245 (16.2) | 41 (2.7) | 10 (0.7) | 1185 (78.4) | ND | 6 (0.4) | ND | 25 (1.7) | |
| PHM | ||||||||||||
| Joneborg et al19 | HM | ND | 3709 | ND | ND | ND | ND | 5164 | ND | 22 | 204 | 20 |
| CHM | ||||||||||||
| PHM | ||||||||||||
| Vargas et al20 | CHM | ND | ND | 1388 | 256 (18.4) | 42 (3.0) | 11 (0.8) | 949 (68.4) | 103 (7.4) | 7 (0.5) | 40 (2.9) | 20 (1.4) |
| PHM | ND | ND | 357 | 64 (17.9) | 12 (3.4) | 2 (0.6) | 260 (72.8) | 8 (2.2) | 1 (0.3) | 4 (1.1) | 10 (2.8) | |
Cong abn, congenital abnormalities; CHM, complete hydatidiform mole; HM, hydatidiform mole; ND, not described; PHM, partial hydatidiform mole; TOP, termination of pregnancy.