Clinicopathological features and prognosis of 60 patients with villoglandular adenocarcinoma*
Clinical features | Value |
Median (IQR) age | 42 (27–68) |
Tumor size (mean±SD) | 2.12±1.78 |
<2 cm | 17 (28.3) |
2–3.9 cm | 25 (41.7) |
≥4 cm | 18 (30.0) |
FIGO stage (2009) | |
IA2 | 4 (6.7) |
IB1 | 39 (65.0) |
IB2 | 11 (18.3) |
IIA1 | 5 (8.3) |
IIA2 | 1 (1.7) |
Primary therapy | |
Surgery | 50 (83.3) |
NACT | 7 (11.7) |
NAIC | 3 (5.0) |
Surgery | |
Radical hysterectomy | 55 (91.7) |
Simple hysterectomy | 5 (8.3) |
Surgical approach | |
Laparoscopy | 23 (38.3) |
Laparotomy | 37 (61.7) |
Adjuvant treatment | |
Radiotherapy | 2 (3.3) |
Chemotherapy | 14 (23.3) |
Radiotherapy and chemotherapy | 10 (16.7) |
None | 34 (56.7) |
Differentiation | |
G1 | 15/35 (42.9) |
G2 | 19/35 (54.3) |
G3 | 1/35 (2.9) |
Unknown | 25 |
Lymphovascular invasion | |
Yes | 2 (3.3) |
No | 58 (96.7) |
Depth of cervical interstitial infiltration | |
≤1/2 | 38/53 (71.7) |
>1/2 | 15/53 (28.3) |
Unknown | 7 |
Uterine infiltration | |
Yes | 4 (6.7) |
No | 56 (93.3) |
Lymph node metastasis | |
Yes | 3 (5.4) |
No | 53 (94.6) |
Unknown | 4 |
Median (IQR) follow-up (month) | 50.2 (5.1–154.6) |
Recurrence/death | 0 |
*Results are number (%) unless stated otherwise.
NACT, neoadjuvant intravenous chemotherapy; ; NAIC, neoadjuvant arterial interventional chemotherapy.