Table 3A

Univariate associates



Variable
Overall survivalLocoregional failureAny failure
HR (95% CI)p-valueHR (95% CI)p-valueHR (95% CI)p-value
Age at diagnosisper 10 years2.85 (1.87 to 4.36)<0.001*1.82 (0.74 to 4.49)0.192.05 (1.15 to 3.66)0.015*
Age at diagnosis≥653.51 (1.54 to 8.02)0.003*4.17 (0.50 to 34.63)0.193.31 (0.95 to 11.51)0.06
<65ReferenceReferenceReference
PathologyClear Cell1.52 (0.44 to 5.20)0.691.53 (0.14 to 16.90)0.621.27 (0.30 to 5.32)0.25
Serous1.07 (0.37 to 3.09)0.65 (0.07 to 5.95)0.52 (0.14 to 1.96)
MixedReferenceReferenceReference
FIGO stageIAReference0.36Reference0.87Reference0.42
IB1.48 (0.65 to 3.38)1.19 (0.14 to 9.88)0.44 (0.06 to 3.30)
Lymphovascular
Space Invasion
Positive1.80 (0.85 to 3.85)0.131.35 (0.26 to 6.99)0.720.81 (0.23 to 2.84)0.74
NegativeReferenceReferenceReference
Sizeper 1 cm1.42 (1.15 to 1.76)<0.001*1.91 (1.20 to 3.02)0.006*1.56 (1.16 to 2.08)0.003*
Size≥3.5 cm2.88 (1.42 to 5.84)0.003*7.02 (0.85 to 58.38)0.073.83 (1.25 to 11.75)0.019
<3.5 cmReferenceReferenceReference
Polyp confinedNoReference0.90Reference0.72Reference0.89
Yes1.07 (0.38 to 3.03)0.57 (0.03 to 12.20)1.11 (0.25 to 4.86)
CytologyPositive2.18 (0.88 to 5.45)0.091.41 (0.16 to 12.29)0.764.36 (1.53 to 12.43)0.006*
NegativeReferenceReferenceReference
Chemotherapy deliveryNo1.16 (0.58 to 2.33)0.679.72 (0.45 to 209.1)0.153.13 (0.90 to 10.90)0.07
YesReferenceReferenceReference
Surgery to first implant≤6 weeks1.39 (0.69 to 2.81)0.361.14 (0.25 to 5.20)0.860.62 (0.23 to 1.64)0.33
>6 weeksReferenceReferenceReference
  • Bold font indicates statistical significance.

  • *Remained significant on multivariate analysis.

  • FIGO, International Federation of Gynecology and Obstetrics.