Studies noted by the International Agency for Research of Cancer 2012 Working Group as primarily establishing a causal connection between asbestos occupational exposure and ovarian cancer21
| Study | Year | Study summary | Pathology reviewed | Comment |
| Acheson et al70 | 1982 | Cohort study, two groups, 757 women exposed to crocodolite fibers (SMR 2.75, 95% CI 1.42 to 4.81) and 570 exposed to chrysotile (SMR 1.48, 95% CI 0.48 to 3.44) | None | None |
| Wignall and Fox71 | 1982 | Cohort study, 500 women with crocodolite exposure (SMR 2.13, p<0.01) | 3/500 samples reviewed. 1/3 ovarian cancer (33%) misdiagnosed, 1 was malignant mesothelioma | Unknown preparation and whether immunostains used prior to 1982 publication date. PAX-8 immunostaining not available at time of publication |
| Berry et al75 | 2000 | Cohort study, 700 women exposed to multiple fiber types (SMR 2.53, 95% CI 1.16 to 4.80) | 6/700 samples reviewed. 2/6 ovarian cancer (33%) misdiagnosed, unknown other pathology | Pathology reviewed in prior papers, either in 196976 or 1985,77 unknown stains used prior to 1969 or 1985. PAX-8 immunostaining not available at time of publication |
| Germani et al72 | 1999 | Cohort study, 631 women from registry of women exposed to any fiber type of asbestos (SMR 4.77, 95% CI 2.1 to 9.06) | None | None |
| Magnani et al73 | 2008 | Cohort study, 777 women exposed to mixed fibers (SMR 2.27, p<0.05) | 9/777 samples reviewed, 2/9 ovarian cancer cases misdiagnosed (22%), unknown other pathology | Unknown if this was pathologic review or by report. Unknown year or immunostains. PAX-8 immunostaining likely not available at time of publication |
SMR, standardized mortality ratio.