Table 4

Cox proportional hazard model

ParameterProgession-free survivalOverall survival
Univariable analysisMultivariable analysisUnivariable analysisMultivariable analysis
HR95% CIP valueHR95% CIP valueHR95% CIP valueHR95% CIP value
Arm (A vs B)1.050.77 to 1.440.7421.130.81 to 1.560.4681.120.76 to 1.660.5591.160.77 to 1.770.461
Age (continuous)1.000.99 to 1.020.5901.000.98 to 1.010.8411.010.99 to 1.030.4271.000.98 to 1.020.841
ECOG performance status1.180.92 to 1.510.1881.120.86 to 1.440.4091.210.91 to 1.60.1931.070.79 to 1.460.639
Stage (III vs IV)1.661.04 to 2.64 0.033 1.500.93 to 2.400.0951.731.00 to 3.000.051.600.91 to 2.800.103
CA125 (continuous)1.001.00 to 1.00 0.003 1.001.00 to 1.00 0.025 1.001.00 to 1.00 <0.0001 1.001.00 to 1.00 0.005
Residual tumor at surgery1.641.37 to 1.97 <0.0001 1.561.29 to 1.88 <0.0001 1.641.34 to 2.01 <0.0001 1.511.22 to 1.86 <0.0001
  • n=169 cases. Bold font indicates statistical significance.

  • χ2 of progression-free survival multivariable model 30.98. χ2 of overall survival multivariable model 28.62.

  • ECOG, Eastern Cooperative Oncology Group.