Parameter | Progession-free survival | Overall survival | ||||||||||
Univariable analysis | Multivariable analysis | Univariable analysis | Multivariable analysis | |||||||||
HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
Arm (A vs B) | 1.05 | 0.77 to 1.44 | 0.742 | 1.13 | 0.81 to 1.56 | 0.468 | 1.12 | 0.76 to 1.66 | 0.559 | 1.16 | 0.77 to 1.77 | 0.461 |
Age (continuous) | 1.00 | 0.99 to 1.02 | 0.590 | 1.00 | 0.98 to 1.01 | 0.841 | 1.01 | 0.99 to 1.03 | 0.427 | 1.00 | 0.98 to 1.02 | 0.841 |
ECOG performance status | 1.18 | 0.92 to 1.51 | 0.188 | 1.12 | 0.86 to 1.44 | 0.409 | 1.21 | 0.91 to 1.6 | 0.193 | 1.07 | 0.79 to 1.46 | 0.639 |
Stage (III vs IV) | 1.66 | 1.04 to 2.64 | 0.033 | 1.50 | 0.93 to 2.40 | 0.095 | 1.73 | 1.00 to 3.00 | 0.05 | 1.60 | 0.91 to 2.80 | 0.103 |
CA125 (continuous) | 1.00 | 1.00 to 1.00 | 0.003 | 1.00 | 1.00 to 1.00 | 0.025 | 1.00 | 1.00 to 1.00 | <0.0001 | 1.00 | 1.00 to 1.00 | 0.005 |
Residual tumor at surgery | 1.64 | 1.37 to 1.97 | <0.0001 | 1.56 | 1.29 to 1.88 | <0.0001 | 1.64 | 1.34 to 2.01 | <0.0001 | 1.51 | 1.22 to 1.86 | <0.0001 |
n=169 cases. Bold font indicates statistical significance.
χ2 of progression-free survival multivariable model 30.98. χ2 of overall survival multivariable model 28.62.
ECOG, Eastern Cooperative Oncology Group.