Post-operative major complications
| Characteristic | Overall (n=158) | Arm A PDS (n=84) | Arm B NACT-IDS (n=74) | P value |
| N (%) | N (%) | N (%) | ||
| Early (≤30 days) | ||||
| Patients with major complications | 46 (29.1) | 39 (46.4) | 7 (9.5) | <0.0001 |
| All events | 269 (100) | 177 (65.8) | 92 (34.2) | |
| Major events | 53 (19.7) | 46 (25.9) | 7 (7.6) | <0.0001* |
| Grade III | 47 (17.5) | 40 (22.6) | 7 (7.6) | 0.002 |
| Grade IV | 3 (1.1) | 3 (1.7) | 0 (0) | 0.209 |
| Grade V | 3 (1.1) | 3 (1.7) | 0 (0) | 0.2019 |
| Late (1–6 months) | ||||
| Patients with major complications | 11 (7.0) | 10 (11.9) | 1 (1.4) | 0.009 |
| All events | 35 (100) | 31 (88.6) | 4 (11.4) | |
| Major events | 14 (40.0) | 13 (41.9) | 1 (25.0) | 0.515* |
| Grade III | 7 (20.0) | 6 (19.3) | 1 (25.0) | 0.791 |
| Grade IV | 3 (8.6) | 3 (9.7) | 0 (0) | 0.588 |
| Grade V | 4 (11.4) | 4 (12.9) | 0 (0) | 0.455 |
Bold font highlights statistically significant differences.
Rates are calculated on all events.
*Major (grades 3, 4, and 5) versus minor (grades 1 and 2) complications.10
IDS, interval debulking surgery; NACT, neoadjuvant chemotherapy; PDS, primary debulking surgery.