Table 1

Mutation prevalence and delays in obtaining results between the genetics referral cohort and the gynecologic oncologist-initiated testing cohort

Genetics referral cohort (January 2014–July 2017)Gynecologic oncologist-initiated genetic testing (August 2017–August 2018)Significance
Patients with HGSC10844
Patients undergoing genetic testing, n (%)54 (50%)38 (86.3%)
Prevalence of germline BRCA mutations, n (%)14 (25.9%)8 (21.1%)
BRCA1 5 (9.2%)5 (13.1%)
BRCA2 9 (16.7%)3 (7.8%)
Median time from diagnosis to genetics consult53 days
(range 3–751 days)
Median time from diagnosis to genetic testing154 days
(range 4–848 days)
40 days
(range 8–175 days)
P<0.01
Median delay between testing and result28.5 days
(range 7–271 days)
8 days
(range 8–48 days)
P=0.002
Median time from diagnosis to result58 days
(range 19–175 days)
P<0.01
  • 186 days (range 15–938 days)

  • P-values obtained with the Mann–Whitney U test for medians

  • *HGSC :high-grade serous ovarian, tubal, or peritoneal carcinoma, BRCA: BReast CAncer gene