Multivariable analysis of survival outcome by adjuvant treatment type compared with observation
| PFS HR (95% CI) | P value | OS HR (95% CI) | P value | |
| Adjuvant therapy | ||||
| OBS | -- | -- | ||
| EBRT | 0.467 (0.22 to 1.01) | 0.054 | 0.47 (0.22 to 0.99) | 0.047 |
| VBT | 0.42 (0.24 to 0.75) | 0.003 | 0.35 (0.20 to 0.60) | <0.001 |
| VBT+C | 0.35 (0.17 to 0.75) | 0.006 | 0.30 (0.14 to 0.65) | 0.002 |
| Stage | ||||
| IA | -- | -- | ||
| IB | 1.92 (1.10 to 3.37) | 0.023 | 2.20 (1.25 to 3.87) | 0.006 |
| II | 2.81 (1.24 to 6.37) | 0.014 | 3.47 (1.53 to 7.85) | 0.003 |
| Grade 2 or 3 | ||||
| Yes | 1.92 (0.87 to 4.21) | 0.10 | 3.03 (1.38 to 6.66) | 0.006 |
| No | -- | -- | ||
| Age | 1.06 (1 to 04 to 1.08) | <0.001 |
C, chemotherapy; EBRT, external beam radiation therapy; OBS, observation; OS, overall survival; PFS, progression-free survival; VBT, vaginal brachytherapy.