Table 1

Summary of 15 patients with suspected minimal deviation adenocarcinoma or carcinoma who underwent immediate hysterectomy

Case No	Age (years)	MRI findings	Cytology	‘Yellow/orange’ mucin	HIK1083 test	Cervical biopsy/ conization	Mode of surgery	Pathological diagnosis
1	55	SP	Adenocarcinoma	–	–	Adenocarcinoma/NA	LRH, BSO, PLN	GAS
2	37	SP	Adenocarcinoma	–	+	GAS/NA	RH, BSO, PLN	GAS
3	77	SP	AGC-FN	NA	NA	MDA/NA	TAH, BSO, PLN, PAN	GAS, MDA
4	42	SP	AGC-NOS	NA	NA	NA/NA	RH, BSO, PLN	MDA
5	49	SP, IP	AGC-FN	+	+	Adenocarcinoma/NA	RH, BSO, PLN, PAN	GAS, MDA, LEGH with atypia, LEGH
6	41	CP	Adenocarcinoma	+	+	Mucinous carcinoma, AIS/AIS	TAH, BSO	GAS, AIS, LEGH with atypia, LEGH
7	46	SP	Adenocarcinoma	NA	+	GAS/NA	RH, BSO, PLN, PAN	GAS, MDA, LEGH
8	52	MP	AGC-FN	+	+	Adenocarcinoma/adenocarcinoma LEGH	TAH, BSO	GAS, LEGH
9	41	SP	AGC-FN	+	+	Adenocarcinoma/NA	RH, BSO, PLN	GAS, UEA
10	62	SP, IP	Adenocarcinoma	NA	NA	Adenocarcinoma/NA	RH, BSO, PLN	Serous carcinoma, LEGH
11	57	SP, IP	NILM	–	–	Normal/NA	TAH, BSO	LEGH with atypia
12	33	MP	AGC-FN	+	+	NA/LEGH with atypia	TAH	LEGH with atypia
13	44	IP	AGC-NOS	+	+	LEGH with atypia/NA	TAH	LEGH with atypia
14	42	CP	AGC-FN	+	+	Normal/LEGH with atypia	TLH	LEGH with atypia
15	47	MP	NILM	–	NA	NA/NA	RH, BSO, PLN	LEGH

AGC-FN, atypical glandular cells-favor neoplastic; AGC-NOS, atypical glandular cells-not otherwise specified; AIS, adenocarcinoma in situ; BSO, bilateral salpingo-oophorectomy; CP, cosmos pattern; GAS, gastric-type mucinous carcinoma; IP, invasion pattern; LEGH, lobular endocervical glandular hyperplasia; LRH, laparoscopic radical hysterectomy; MDA, minimal deviation adenocarcinoma; MP, microcystic pattern; MRI, magnetic resonance imaging; NA, not available; NILM, negative for intraepithelial lesion or malignancy; PAN, para-aortic lymphadenectomy; PLN, pelvic lymphadenectomy; RH, radical hysterectomy; SP, solid pattern; TAH, total abdominal hysterectomy; TLH, total laparoscopic hysterectomy; UEA, usual-type endocervical adenocarcinoma.