Table 1

Clinicopathological characteristics of patients with International Federation of Gynecology and Obstetrics (FIGO) stage I uterine serous carcinoma confined to the endometrium stratified by type of adjuvant treatment

CharacteristicObservation (n=833)CT only (n=353)RT only (n=175)CRT (n=348)P value
Age (years)0.001
 <65329 (39.5%)174 (49.3%)64 (36.6%)165 (47.4%)
 ≥65504 (60.5%)179 (50.7%)111 (63.4%)183 (52.6%)
Race0.2
 White618 (74.2%)252 (71.4%)131 (74.9%)246 (70.7%)
 Black170 (20.4%)75 (21.2%)39 (22.3%)87 (25%)
 Other/Unknown45 (5.4%)26 (7.4%)(2.9%)*15 (4.3%)
Co-morbidities0.061
 No617 (74.1%)280 (79.3%)141 (80.6%)276 (79.3%)
 Yes216 (25.9%)73 (20.7%)34 (19.4%)72 (20.7%)
History of another tumor0.74
 No663 (79.6%)275 (77.9%)143 (81.7%)280 (80.5%)
 Yes170 (20.4%)78 (22.1%)32 (18.3%)68 (19.5%)
Insurance0.002
 Private343 (41.2%)177 (50.1%)62 (35.4%)175 (50.3%)
 Government478 (57.4%)168 (47.6%)110 (62.9%)169 (48.6%)
 Uninsured/Unknown12 (1.4%)(2.3%)*(1.7%)*(1.1%)*
Reporting facility0.005
 Academic428 (51.4%)192 (54.4%)108 (61.7%)212 (61.3%)
 Non-academic404 (48.6%)161 (45.6%)67 (38.3%)134 (38.7%)
Tumor size (cm)0.03
 <2301 (36.1%)127 (36%)62 (35.4%)125 (35.9%)
 ≥2221 (26.5%)126 (35.7%)54 (30.9%)95 (27.3%)
 Unknown311 (37.3%)100 (28.3%)59 (33.7%)128 (36.8%)
Para-aortic LND0.002
 No120 (24.6%)77 (29.2%)27 (24.1%)41 (15.3%)
 Yes368 (75.4%)187 (70.8%)85 (75.9%)227 (84.7%)
Omentectomy0.028
 No210 (48.1%)124 (51%)41 (41.4%)91 (38.7%)
 Yes227 (51.9%)119 (49%)58 (58.6%)144 (61.3%)
Approach0.38
 MIS297 (63.9%)151 (64.3%)60 (63.2%)145 (66.2%)
 Open168 (36.1%)84 (35.7%)35 (36.8%)74 (33.8%)
  • *n<10. Missing values: approach 695 cases, facility type 3 cases, PaLND 577 cases, omentectomy 695 cases.

  • CRT, chemotherapy and radiation therapy; CT, chemotherapy; Hx, history; LND, lymph node dissection/sampling; MIS, minimally invasive surgery; PaLND, para-aortic lymph node dissection; RT, radiation therapy.