Table 2

Biomarker staining

Biomarkern (%)
MMR, all subtypes
 Intact28 (100)
 Deficient0
PD-L1
 Pure neuroendocrine
  Positive2 (8)
  Negative23 (92)
 Mixed
  Positive3 (50)
  Negative3 (50)
SST, small cell
 Positive1 (5)
 Negative18 (95)
PARP-1, small cell
 High6 (55)
 Moderate4 (36)
 Low0
 Negative1 (9)
  • H-score ≥100 is high and H-score 40–100 is moderate.

  • MMR, mismatch repair; PARP-1, Poly-(ADP-ribose) polymerase 1; PD-L1, programmed death-ligand 1; SST, somatostatin.