Cox regression analysis for overall survival using univariable and two-variable models in patients with locally advanced cervical cancer after Okabayashi–Kobayashi radical hysterectomyUnivariable Cox regression analysis for each variable was performed, and then a two-variable regression model based on the number of observed events was obtained. Adeno(squamous)carcinoma: adenocarcinoma/adenosquamous carcinoma.
| Risk factors | N | Death | Cox regression analysis for OS in LACC | |||
| Univariable HR (95% CI) | P value | Two-variable model HR (95% CI) | P -value | |||
| Histology | ||||||
| Squamous | 29 | 3 | Ref | 0.003 | Ref | 0.002 |
| Adeno(squamous)carcinoma | 16 | 9 | 7.5 (2.0 to 28.1) | 8.9 (2.3 to 34.4) | ||
| pT classification | ||||||
| pT1b | 25 | 3 | Ref | 0.02 | ||
| pT2 | 20 | 9 | 5.0 (1.3 to 18.4) | |||
| Lymph node metastasis | ||||||
| Negative | 24 | 2 | Ref | 0.001 | Ref | 0.008 |
| Positive | 21 | 10 | 6.8 (1.5 to 31.2) | 7.9 (1.7 to 36.7) | ||
| Lymphovascular space invasion | ||||||
| Negative | 16 | 3 | Ref | 0.4 | ||
| Positive | 29 | 9 | 1.8 (0.5 to 6.5) | |||
Ref, reference.
LACC, locally advanced cervical cancer; OS, overall survival.