Table 2

Exclusion criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:
1.history of previous malignancy treated with chemotherapy
2.history of previous malignancy within 5 years prior to inclusion, with the exception of carcinoma in situ of the cervix, radically excised basal cell, or squamous cell cancer of the skin or synchronal endometrial carcinoma FIGO IA G1/2
3.if complete primary cytoreduction is not feasible, for the following reasons:
a. diffuse deep infiltration of the root of small bowel mesentery, and/or;
b. diffuse carcinomatosis of the small bowel that requires resection that leads to short bowel syndrome (remaining bowel <1.5 meter), and/or;
c. diffuse involvement/deep infiltration of stomach/duodenum, and/or;
d. diffuse involvement/deep infiltration of head or middle part of pancreas, and/or;
e. involvement of truncus coeliacus, hepatic arteries or left gastric artery, and/or;
f. non-resectable enlarged (larger than 10 mm short axis) lymph nodes case of a known psychiatric disorder, substance abuse disorder, or high suspicion of a mental disorder that could interfere with cooperation or compliance with the requirements of the trial
5.when opting for fertility sparing surgery case of a known history of human immunodeficiency virus (HIV, or HIV 1/2 antibodies) case of known active hepatitis B (eg, HBsAg reactive) or hepatitis C (eg, HCV RNA (qualitative))
8.patients who received prior treatment for the current malignancy