Clinicopathologic features of the ultra-low risk endometrioid endometrial cancer patients included in the study
| Clinicopathologic feature | All patients (n=486) (n (%)) | Non-recurrent (n=472) (n (%)) | Recurrent (n=14) (n (%)) | P value |
| Age (years) (median, range) | 58 (28–91) | 57 (28–91) | 65 (40–84) | 0.025 |
| BMI (kg/m2) (median) | 31 (16–69) | 31 (16–67) | 28 (21–31) | ≤0.001 |
| Race | ||||
| White | 403 (83) | 392 (83) | 11 (79) | ≤0.001 |
| African American | 17 (4) | 17 (4) | 0 (0) | |
| Hispanic | 2 (0.4) | 1 (0.2) | 1 (7) | |
| Asian | 38 (8) | 38 (8) | 0 (0) | |
| Other | 11 (2) | 11 (2) | 0 (0) | |
| Not answered | 15 (3) | 13 (3) | 2 (14) | |
| Type of surgical approach | ||||
| Open surgery | 34 (7) | 33 (7.0) | 1 (7.1) | 0.389 |
| Minimally invasive surgery | 452 (93) | 439 (93) | 13 (93) | |
| Lymph nodes | ||||
| Sentinel LN mapping | 345 (71) | 333 (71) | 12 (86) | 0.101 |
| Total LN dissection | 106 (22) | 106 (23) | 0 (0) | |
| None* | 35 (7) | 33 (7) | 2 (14) | |
| Pelvic washing status | ||||
| Positive | 21 (4) | 20 (4) | 1 (7) | 0.852 |
| Negative | 411 (85) | 420 (89) | 13 (93) | |
| Not done | 54 (11) | 32 (7) | 0 (0) | |
| DNA mismatch repair protein IHC | ||||
| Not performed | 275 (56) | 266 (56) | 9 (64) | 0.214 |
| Proficient | 158 (33) | 156 (33) | 2 (14) | |
| Deficient | 53 (11) | 50 (11) | 3 (22) | |
| MLH1 hypermethylation | 23 | 20 | 3 | |
| Lynch syndrome testing | ||||
| Testing not done | 437 (90) | 426 (90) | 11 (79) | 0.170 |
| Testing done | 49 (10) | 46 (10) | 3 (21) | |
| Testing positive for Lynch | 10 | 10 | 0 |
*For patients who did not undergo lymph node dissection, the Mayo criteria were used intra-operatively to decide if lymphadenectomy should be performed.21
BMI, body mass index; IHC, immunohistochemistry; LN, lymph node.