Multivariable survival analysis by age of diagnosis
| Factor | Events (n (%)) | Progression-free survival (%) (95% CI) | HR (95% CI) | P value |
| Age of diagnosis (years) | ||||
| ≤40 | 23 (22) | 74.9 (65.2 to 84.5) | 3.96 (2.17 to 7.22) | <0.001 |
| 41–60 | 40 (9) | 80.7 (71.7 to 89.7) | – | |
| Grade | ||||
| 1 | 21 (6) | 89.0 (82.2 to 95.9) | – | |
| 2 | 14 (11) | 79.7 (66.0 to 93.3) | 1.25 (0.58 to 2.72) | 0.57 |
| 3 | 19 (30) | 60.9 (44.4 to 77.4) | 4.29 (1.96 to 9.40) | <0.001 |
| LVSI | ||||
| Positive | 33 (23) | 69.2 (58.3 to 80.0) | 2.69 (1.38 to 5.26) | 0.004 |
| Negative | 24 (6) | 89.9 (84.0 to 95.7) | – |
Values in bold italic type…
CI, confidence interval; HR, hazard ratio; LVSI, lymphovascular space invasion.