Age and clinical characteristics of the study groups
| Variables |
BRCA-negative (n=66) |
BRCA1-positive (n=32) |
BRCA2-positive (n=37) | P value |
| Age at AMH analysis, years, mean±SD | 32.7±7.3 | 32.6±6.2 | 32.1±6.2 | 0.909 |
| Current age, years, mean±SD | 41.6±7.6 | 41.4±6.4 | 41.1±6.4 | 0.923 |
| Active smokers at AMH analysis | 26 (39.4) | 12 (37.5) | 13 (35.1) | 0.912 |
| Body mass index, kg/m2, mean±SD | 22.3±3.02 | 24±5.1 | 22.6±5.9 | 0.201 |
| Serum AMH levels, ng/mL, mean±SD | 2.27±2.03 | 3±2.27 | 2.54±2.07 | 0.280 |
| Ovarian response* | 0.092 | |||
| Low | 12 (18.2) | 6 (18.8) | 7 (18.9) | |
| Normal | 20 (30.3) | 2 (6.25) | 7 (18.9) | |
| High | 34 (51.5) | 24 (75) | 23 (62.2) |
Data as frequencies and percentages in parenthesis unless otherwise stated.
*Low: AMH level ≤0.58 ng/mL; normal: AMH level >0.58 and ≤1.48 ng/mL; high: AMH level >1.48 ng/mL.
AMH, anti-müllerian hormone.