Table 2

Comparison of peri-operative and 30-day surgical outcomes between systematic PLD and SLN biopsy groups

CharacteristicUnadjusted cohort*IPTW-adjusted cohort†
PLD
(n=198)
SLN biopsy
(n=188)
p value‡PLD
(n=198)
SLN biopsy
(n=188)
p value‡
Any intra-operative complication4 (2.0)1 (0.5)0.232.0%0.4%0.19
Conversion to open operation§2 (1.0)1 (0.5)0.601.0%0.8%0.83
Post-operative complications within 30 days
 ASC grade ≥215 (7.6)9 (4.8)0.266.3%4.7%0.50
 ASC grade ≥33 (1.5)1 (0.5)0.361.2%0.5%0.49
Re-admission within 30 days7 (3.5)4 (2.1)0.412.7%1.9%0.61
Re-operation within 30 days2 (1.0)0.0 (0.0)0.310.8%0.0 (0.0)0.39
Operative time, mean (SD), min225.3 (71.4)136.6 (42.0)<0.001222.8 (70.1)138.0 (44.0)<0.001
EBL, median (IQR), mL100 (60–200)50 (50–100)<0.001100 (50–200)50 (50–100)<0.001
Length of hospital stay, days
 ≥246 (23.2)15 (8.0)<0.00121.6%7.8%<0.001
 ≥314 (7.1)9 (4.8)0.356.9%4.9%0.40
Length of hospital stay after ERAS protocol implementation, days
 ≥223/119 (19.3)15/188 (8.0)0.00419.2%7.8%0.004
 ≥36/119 (5.0)9/188 (4.8)0.925.5%4.9%0.82
  • *Results are reported as number (%) of patients unless stated otherwise.

  • †Results are reported as weighted mean (SD), weighted median (IQR), or weighted percentage.

  • ‡Comparisons between groups were evaluated with a logistic regression model for binary outcomes and a linear regression model for continuous outcomes. EBL was analyzed after application of a logarithmic transformation.

  • §Conversions to open operation in the PLD group were for staging. The only conversion in the SLN group was for hysterectomy.

  • ASC, Accordion Severity Classification; EBL, estimated blood loss; ERAS, Enhanced Recovery After Surgery; IPTW, inverse probability of treatment weighting; IQR, interquartile range; PLD, pelvic lymphadenectomy; SLN, sentinel lymph node.