Distribution of molecular subgroups among histopathological types. G: grade; MMMT: Malignant Mixed Müllerian Tumor
| Histological type | MMR-D on IHC | POLE-EDM | p53 abnormal | p53 wild type | MMR-D + POLE-EDM | POLE-EDM + p53 abnormal |
|---|---|---|---|---|---|---|
| G1-2 Endometrioid EC (n=64) | 21 | 2 | 3 | 38 | 0 | 0 |
| G3 Endometrioid EC (n=5) | 3 | 0 | 0 | 1 | 1 | 0 |
| Serous EC (n=11) | 1 | 0 | 10 | 0 | 0 | 0 |
| Clear cell EC (n=3) | 0 | 0 | 1 | 1 | 1 | 0 |
| Mixed G3 Endometrioid and serous EC (n=4) | 0 | 0 | 2 | 0 | 1 | 1 |
| MMMT EC (n=6) | 0 | 0 | 6 | 0 | 0 | 0 |
| Total (n=93) | 25 (27%) | 2 (2%) | 22 (24%) | 40 (43%) | 3 (3%) | 1 (1%) |