Table 3

Multiple regression analysis of disease-free survival and overall survival in patients with stage IIIA endometrial cancer

VariableDisease-free survivalOverall survival
Univariate analysisMultivariate analysisUnivariate analysisMultivariate analysis
HR95% CIP valuesHR95% CIP valuesHR95% CIP valuesHR95% CIP values
Age, years (≤60 vs >61)0.580.38 to 0.840.040.580.34 to 0.970.0050.760.48 to 1.210.25
Type of surgery (LT vs LS)0.720.37 to 1.370.320.710.33 to 1.550.25
Grade (1 vs 3)0.650.36 to 1.160.160.890.46 to 1.730.644
Grade (2 vs 3)0.700.47 to 1.060.780.47 to 1.30
Lymphovascular space invasion (negative vs positive)0.570.36 to 0.900.020.710.38 to 1.300.340.540.30 to 0.970.040.730.37 to 1.430.37
Peritoneal cytology (negative vs positive)0.830.48 to 1.420.490.550.30 to 1.010.050.450.23 to 0.860.02
Myometrial invasion (<50% vs >50%)0.510.31 to 0.830.0070.570.29 to 1.140.130.450.23 to 0.850.010.500.21 to 1.030.09
Cervical involvement (no vs yes)0.650.44 to 0.950.021.010.59 to 1.730.940.500.31 to 0.800.0040.940.49 to 1.710.79
Lymphadenectomy (yes vs no)0.810.41 to 1.370.090.520.30 to 0.910.0070.330.16 to 0.770.001
Adjuvant therapy0.120.48
Radiotherapy vs chemoradiation1.180.74 to 1.891.350.79 to 2.32
Chemotherapy vs chemoradiation1.641.02 to 2.641.300.71 to 2.38
  • LS, laparoscopy; LT, laparotomy.