Table 4

Multiple regression analysis of disease-free survival and overall survival in patients with stage IIIC endometrial cancer

Variable	Disease-free survival						Overall survival
	Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
	HR	95% CI	P values	HR	95% CI	P values	HR	95% CI	P values	HR	95% CI	P values
Age, years (≤60 vs >61)	0.58	0.45 to 0.76	<0.0001	0.63	0.49 to 0.83	0.001	0.45	0.33 to 0.62	<0.0001	0.50	0.36 to 0.69	<0.0001
Type of surgery (LT vs LS)	1.09	0.66 to 1.82	0.72				1.08	0.60 to 1.94	0.80
Grade (1 vs 3)	0.59	0.40 to 0.86	0.002	0.66	0.45 to 0.96	0.01	0.49	0.31 to 0.79	0.001	0.59	0.37 to 0.94	0.014
Grade (2 vs 3)	0.64	0.49 to 0.85	0.002	0.70	0.53 to 0.92	0.01	0.59	0.42 to 0.80	0.001	0.65	0.46 to 0.91	0.014
Lymphovascular space invasion (negative vs positive)	0.85	0.58 to 1.23	0.38				0.74	0.46 to 1.18	0.21
Peritoneal cytology (negative vs positive)	1.04	0.66 to 1.62	0.86				1.00	0.59 to 1.70	0.98
Myometrial invasion (<50% vs >50%)	0.56	0.39 to 0.80	0.001	0.62	0.44 to 0.89	0.008	0.58	0.38 to 0.88	0.01	0.69	0.45 to 1.05	0.08
Cervical involvement (no vs yes)	0.65	0.50 to 0.84	0.001	0.65	0.50 to 0.85	0.001	0.62	0.46 to 0.85	0.004	0.63	0.46 to 0.86	0.004
PALND (no vs yes)	1.84	1.35 to 2.51	<0.0001	1.88	1.38 to 2.58	<0.0001	1.96	1.37 to 2.81	<0.0001	2.02	1.40 to 2.90	<0.0001
Adjuvant therapy			0.238						0.09
Radiotherapy vs chemoradiation	0.86	0.59 to 1.25					0.62	0.38 to 1.00
Chemotherapy vs chemoradiation	1.21	0.90 to 1.61					1.10	0.78 to 1.57