RT Journal Article
SR Electronic
T1 Ovarian Sentinel Node: Is It Feasible?
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 568
OP 572
DO 10.1097/IGC.0b013e318211ef75
VO 21
IS 3
A1 Nyberg, Reita H.
A1 Korkola, Pasi
A1 Mäenpää, Johanna
YR 2011
UL http://ijgc.bmj.com/content/21/3/568.abstract
AB Objective To examine whether the intraoperative combined injection technique is feasible in locating the sentinel node(s) of the ovary.Methods/Materials In 16 patients with high-risk uterine cancer and normal postmenopausal ovaries, technetium isotope and blue dye were injected in the right or left ovary during laparotomy, respectively. During the operation, the pelvic and para-aortic lymphatic areas were searched, and the number, method of detection, and location(s) of the hot and/or blue node(s) were recorded.Results One to 3 sentinel nodes per patient were identified in all but 1 patient (15 of 16, 94%). The sentinel nodes (n = 30) were all located in the para-aortic area. The sentinel nodes of the left ovary were mainly (9 of 14, 64%) located above the inferior mesenteric artery level, as the most sentinel nodes of the right ovary (15 of 16, 94%) were found below the inferior mesenteric artery level (P = 0.001). There were no contralateral or bilateral sentinel nodes.Conclusions The combined intraoperative injection technique with radioisotope and blue dye is fast enough to identify the ovarian sentinel node(s). The stained nodes were consistently located on a certain lymphatic area. The sentinel node concept for the early ovarian cancer deserves more attention.