PT - JOURNAL ARTICLE AU - Q. D. Pieterse AU - C. P. Maas AU - M. M. Ter Kuile AU - M. Lowik AU - M. A. Van Eijkeren AU - J. B.M.Z. Trimbos AU - G. G. Kenter TI - An observational longitudinal study to evaluate miction, defecation, and sexual function after radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer AID - 10.1136/ijgc-00009577-200605000-00027 DP - 2006 Apr 01 TA - International Journal of Gynecologic Cancer PG - 1119--1129 VI - 16 IP - 3 4099 - http://ijgc.bmj.com/content/16/3/1119.short 4100 - http://ijgc.bmj.com/content/16/3/1119.full SO - Int J Gynecol Cancer2006 Apr 01; 16 AB - The objective of this study was to evaluate the problems with miction, defecation, and sexuality after a radical hysterectomy with or without adjuvant radiotherapy for the treatment of cervical cancer stage I–IIA. This study included an observational longitudinal study of self-reported bladder, defecation, and sexual problems with a baseline score. Ninety-four women were included in the study. An age-matched control group consisted of 224 women. The patients showed significantly more negative effects on sexual function compared with both the controls and their situation before the treatment throughout 24 months of follow-up. The problems included less lubrication, a narrow and short vagina, senseless areas around the labia, dyspareunia, and sexual dissatisfaction. Up to 12 months after the treatment, the patients complained significantly more of little or no urge to urinate and diarrhea as compared with the controls. Adjuvant radiotherapy did not increase the risk of bladder dysfunction, colorectal motility disorders, and sexual functions. We conclude that a radical hysterectomy for the treatment of early-stage cervical carcinoma is associated with adverse effects mainly on sexual functioning.