RT Journal Article SR Electronic T1 Recurrent ovarian cancer metastatic to the sternum, costae, and thoracic wall after prolonged treatment with platinum-based chemotherapy: a case report and review of the literature JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP 299 OP 303 DO 10.1136/ijgc-00009577-200602001-00049 VO 16 IS Suppl 1 A1 G. Pavlakis A1 G. Mountzios A1 E. Terpos A1 A. Leivaditou A1 G. Papadopoulos A1 P. Papasavas YR 2006 UL http://ijgc.bmj.com/content/16/Suppl_1/299.abstract AB Sternal and costal metastases from ovarian cancer are extremely rare. We present here a case of a 47-year-old woman with thoracic wall metastasis from serous–papillary ovarian carcinoma that occurred 3 years after the initial diagnosis, although the patient had received various regimens of intense platinum-based chemotherapy. Special emphasis is given to the effects of alkylating agents, such as cisplatin and carboplatin, on the pattern of tumor spread. We also discuss the possible mechanisms through which the biologic and metastatic behavior of this tumor is expressed.