RT Journal Article SR Electronic T1 Successful pregnancy after localized resection of perforated uterus in choriocarcinoma and a literature review JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP 445 OP 448 DO 10.1136/ijgc-00009577-200602001-00084 VO 16 IS Suppl 1 A1 Behtash, N. A1 Ansari, S. A1 Sarvi, F. YR 2006 UL http://ijgc.bmj.com/content/16/Suppl_1/445.abstract AB Choriocarcinoma is an aggressive neoplasm arising in the body of the uterus. Rapid growth and myometrial invasion may be followed by uterine perforation. In this study, we present the cases of two young patients (18 and 19 years of age) with acute abdominal pain and shock, while they were under chemotherapy due to persistent trophoblastic disease. During emergent exploratory laparotomy, localized resection of uterus was performed. They had their first successful term pregnancy 5 and 4 years after surgery, respectively. Uterine perforation following choriocarcinoma is a rare event. Hysterectomy is recommended in emergency conditions, but localized resection of uterus should be considered in women who are desirous of future fertility.