PT - JOURNAL ARTICLE AU - Behtash, N. AU - Ansari, S. AU - Sarvi, F. TI - Successful pregnancy after localized resection of perforated uterus in choriocarcinoma and a literature review AID - 10.1136/ijgc-00009577-200602001-00084 DP - 2006 Jan 01 TA - International Journal of Gynecologic Cancer PG - 445--448 VI - 16 IP - Suppl 1 4099 - http://ijgc.bmj.com/content/16/Suppl_1/445.short 4100 - http://ijgc.bmj.com/content/16/Suppl_1/445.full SO - Int J Gynecol Cancer2006 Jan 01; 16 AB - Choriocarcinoma is an aggressive neoplasm arising in the body of the uterus. Rapid growth and myometrial invasion may be followed by uterine perforation. In this study, we present the cases of two young patients (18 and 19 years of age) with acute abdominal pain and shock, while they were under chemotherapy due to persistent trophoblastic disease. During emergent exploratory laparotomy, localized resection of uterus was performed. They had their first successful term pregnancy 5 and 4 years after surgery, respectively. Uterine perforation following choriocarcinoma is a rare event. Hysterectomy is recommended in emergency conditions, but localized resection of uterus should be considered in women who are desirous of future fertility.