TY - JOUR T1 - Statistical analysis of pathologic risk factors for intramyometrial lymphvascular space involvement in myoinvasive endometrial carcinoma JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 1330 LP - 1335 DO - 10.1136/ijgc-00009577-200605000-00057 VL - 16 IS - 3 AU - L. H. Honorè AU - J. Hanson Y1 - 2006/04/01 UR - http://ijgc.bmj.com/content/16/3/1330.abstract N2 - In a retrospective study using univariate analysis, we identified tumor type (nonendometrioid vs endometrioid), depth of myoinvasion (MI), mode of MI (infiltrative vs cohesive), and direct anatomic invasion of the cervical wall from the isthmus as significant positive risk factors for intramyometrial lymphvascular space involvement (LVSI). On multivariate analysis, tumor grade, depth of MI, and mode of MI retained their significance. We created a grid for the relative risks of LVSI with respect to these variables individually or in combination. We suggest that our indirect estimate of the risk of LVSI can help in assessing prognosis and determining the need for adjuvant therapy whenever LVSI is important in clinical decision making, but its pathologic diagnosis is uncertain. ER -