%0 Journal Article %A M. A. Bookman %A B. E. Greer %A R. F. Ozols %T Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel vs. cisplatin and paclitaxel (GOG 158) and an update on GOG0 182-ICON5 %D 2003 %R 10.1136/ijgc-00009577-200311000-00002 %J International Journal of Gynecologic Cancer %P 735-740 %V 13 %N 6 %X Mature results from GOG158 have clearly established carboplatin and paclitaxel as an effective and well tolerated standard regimen, providing a basis for the reference arm in GOG0182-ICON5, an ongoing multiarmed phase III trial of the Gynecologic Cancer InterGroup (GCIG) evaluating the incorporation of newer cytotoxic agents. Results from GOG158 will be reviewed, including an analysis of second-look surgical outcomes, followed by an update on the current status of GOG0182-ICON5. %U https://ijgc.bmj.com/content/ijgc/13/6/735.full.pdf